Grant: Research Tools and Instruments - Category 1 (<$150,000)
York University
$80,005.00
Structural biology facility
FY 2007-08
Summary
Funds to purchase a stereomicroscope and a preparative centrifuge are requested. The preparative centrifuge will be used to harvest cell cultures containing recombinant proteins and to separate recombinant proteins from cellular debris. The stereomicroscope will be used to observe protein crystals during crystallization setups. The abilities to harvest cells, separate recombinant proteins and most importantly to observe protein crystals is fundamental for the success of the NSERC Discovery research project. The focus of the research program is to use macromolecular crystallography to characterize deubiquitination in yeast including the determination of tertiary structures of ubiquitin specific proteases and the characterization of the mechanism of interaction between ubiquitin specific proteases and their target proteins. This equipment will be made available to other members of the department and will be instrumental in the training of highly qualified personnel.
Program
Research Tools and Instruments - Category 1 (<$150,000)
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
345639-2007
Name nom
Saridakis, Vivian
Department département
Biology
Organization id
38
Institution établissement
York University
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2007
Competition year année de concours
2007
Award amount
80005
Program id
EQPEQ
Program name en
Research Tools and Instruments - Category 1 (<$150,000)
Program name fr
Outils et instruments de recherche - catégorie 1 (<150 000$)
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
32
Committee name en
Cell Biology
Committee name fr
Biologie cellulaire
Area of application code
1200
Area of application group en
Advancement of knowledge
Area of application group fr
Avancement des connaissances
Area of application en
Advancement of knowledge
Area of application fr
Avancement des connaissances
Research subject code
5400
Research subject group en
Biochemistry
Research subject group fr
Biochimie
Research subject en
Biochemistry
Research subject fr
Biochimie
Partie
1
Nb partie
1
Application title
Structural biology facility
Keyword
NA
Application summary
Funds to purchase a stereomicroscope and a preparative centrifuge are requested. The preparative centrifuge will be used to harvest cell cultures containing recombinant proteins and to separate recombinant proteins from cellular debris. The stereomicroscope will be used to observe protein crystals during crystallization setups. The abilities to harvest cells, separate recombinant proteins and most importantly to observe protein crystals is fundamental for the success of the NSERC Discovery research project. The focus of the research program is to use macromolecular crystallography to characterize deubiquitination in yeast including the determination of tertiary structures of ubiquitin specific proteases and the characterization of the mechanism of interaction between ubiquitin specific proteases and their target proteins. This equipment will be made available to other members of the department and will be instrumental in the training of highly qualified personnel.
