Grant: Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships
University of Alberta
$105,000.00
Structure and function studies on the human sodium proton exchanger isoform 1, an important link in cardiovascular disease and cancer
FY 2009-10
Summary
Cardiovascular disease and cancer are two of the biggest health issues facing Canadians today. In order to develop safer and more effective therapies for these conditions we must first understand how the body responds in these conditions. This project aims to understand, on a molecular level, the structure and function of the sodium proton exchanger isoform 1 (NHE1). NHE1 is known to be directly involved in heart disease as well as tumour metastasis. Our lab has developed a system, wherein we can study both the structure and the function of the human protein in a purified environment. These experiments will lay the groundwork for the development of safer and more effective therapies for heart disease and cancer.
Department
Program
Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships
Recipient
Location
Alberta, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
206149
Name
Kemp Grant A
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Circulatory and Respiratory Health
Theme2
Biomedical
Prcname2
Doctoral Research Awards - A
Projecttitle
Structure and function studies on the human sodium proton exchanger isoform 1, an important link in cardiovascular disease and cancer
Programtype2
Studentship Programs
Orgnameinp2
University of Alberta
Cihramount2
$105,000
Cihrequipment2
$0
Programname2
Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships
Keyworddelim
Biochemistry; Cardiovascular Research; Electron Microscopy; Membrane Proteins; Membrane Transport; Oncology; Structural Biology
Abstract
Cardiovascular disease and cancer are two of the biggest health issues facing Canadians today. In order to develop safer and more effective therapies for these conditions we must first understand how the body responds in these conditions. This project aims to understand, on a molecular level, the structure and function of the sodium proton exchanger isoform 1 (NHE1). NHE1 is known to be directly involved in heart disease as well as tumour metastasis. Our lab has developed a system, wherein we can study both the structure and the function of the human protein in a purified environment. These experiments will lay the groundwork for the development of safer and more effective therapies for heart disease and cancer.
Competitiondate
200910
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Kemp, Grant A
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $105,000~ $0~
