Grant: Project Grant
University of Toronto
$998,326.00
Molecular events governing the abscission checkpoint
FY 2024-25
Summary
It is vital that when a cell divides into two new cells that each of the new cells has a complete copy of the genome. Failure to do this results in cells with mutations that go on to from tumors. The last step in the cell division process is the final point where a cell can choose not to divide if it detects errors. The goal of this study is to determine how those errors are interpreted by the cell into decision to stop cell division.
Department
Program
Project Grant
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
522892
Name
Wilde Andrew R
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Cell Biology - Molecular/Fundamental
Projecttitle
Molecular events governing the abscission checkpoint
Programtype2
Operating Grants
Orgnameinp2
University of Toronto
Cihramount2
$998,326
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Cell Division; Cytokinesis; Kinase; Mitosis; Phosphatase
Abstract
It is vital that when a cell divides into two new cells that each of the new cells has a complete copy of the genome. Failure to do this results in cells with mutations that go on to from tumors. The last step in the cell division process is the final point where a cell can choose not to divide if it detects errors. The goal of this study is to determine how those errors are interpreted by the cell into decision to stop cell division.
Competitiondate
202503
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Wilde, Andrew R
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $998,326~ $0~
