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Grant: Project Grant

McMaster University

$699,976.00

A Degradable Sustained Release Mucoadhesive Drug Delivery System to Regulate Intraocular Pressure (IOP) in Glaucoma

FY 2019-20

Summary
Glaucoma is an eye disease, which is a leading cause of visual disability in the United States (more than 2.7 million cases) and throughout the world (more than 60 million cases). An important impediment towards the inability to reduce intraocular pressure (IOP) and prevent the progression of glaucoma is the inability of the patients to comply with the prescription. The goals of this proposal are to investigate the efficacy of our novel sustained release mucoadhesive drug delivery technology on a newly developed glaucoma mouse model. This research would prove useful in developing strategies to counter the patient compliance issue for patients suffering from Glaucoma.
Program
Project Grant
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
420357
Name
Sheardown Heather D
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Aging
Theme2
Biomedical
Prcname2
Biomedical Engineering
Projecttitle
A Degradable Sustained Release Mucoadhesive Drug Delivery System to Regulate Intraocular Pressure (IOP) in Glaucoma
Programtype2
Operating Grants
Orgnameinp2
McMaster University
Cihramount2
$699,976
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Drug Delivery; Drug Release; Genetic Mouse Models; Glaucoma; Intraocular Pressure; Latanoprost; Mucoadhesive Micelle
Abstract
Glaucoma is an eye disease, which is a leading cause of visual disability in the United States (more than 2.7 million cases) and throughout the world (more than 60 million cases). An important impediment towards the inability to reduce intraocular pressure (IOP) and prevent the progression of glaucoma is the inability of the patients to comply with the prescription. The goals of this proposal are to investigate the efficacy of our novel sustained release mucoadhesive drug delivery technology on a newly developed glaucoma mouse model. This research would prove useful in developing strategies to counter the patient compliance issue for patients suffering from Glaucoma.
Competitiondate
202003
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Sheardown, Heather D
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $699,976~ $0~