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Contribution: Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology

University of Calgary|University of Calgary

$1,844,386.95

The effect of long-duration space flight on bone microarchitecture and strength using three-dimensional high resolution imaging.

FY 2019-20 · 2019-09-12

Summary
The effect of long-duration space flight on bone microarchitecture and strength using three-dimensional high resolution imaging. Our bones continually adapt to support our body weight in a gravity environment. Bones become weaker when everyday stresses are reduced. Astronauts lose bone strenght rapidly while in space due to weightlessness and reduced exercise. The purpose of this study is to understand the time-course of bone strength loss in space. We will use high resolution bone imaging to investigate how long it takes for bone loss to stabilize in space and whether stabilization differs between first-time and repeat flier astronauts. Results will help understand how to ensure astronauts remain healthier on longer-duration missions and the risks of very long spaceflights in the future.
Program
Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology
Location
Calgary|Calgary, Alberta, Canada
Recipient Type
Academia
Type
Contribution
Source
Proactive Disclosure - Grants and Contributions

Amendments

Each version of the agreement as published, oldest first, with its total as of that version. The amount above is the latest.

AmendmentDateFiscal YearTotal
02019-09-122019-20$870,618.00
12019-09-122019-20$805,965.29
22019-09-122019-20$1,844,386.95

As published

Additional Information
The amount allocated covers more than one fiscal year
Additional Information (French)
La somme allouée couvre plus d'un exercice financier.
Agreement End Date
2031-03-31
Agreement Number
19NASAHER1
Agreement Start Date
2019-09-12
Agreement Title
The effect of long-duration space flight on bone microarchitecture and strength using three-dimensional high resolution imaging.
Agreement Title (French)
The effect of long-duration space flight on bone microarchitecture and strength using three-dimensional high resolution imaging.
Agreement Type
Contribution
Agreement Value
$1,844,386.95
Amendment Date
2026-01-30
Amendment Number
2
Description
The effect of long-duration space flight on bone microarchitecture and strength using three-dimensional high resolution imaging. Our bones continually adapt to support our body weight in a gravity environment. Bones become weaker when everyday stresses are reduced. Astronauts lose bone strenght rapidly while in space due to weightlessness and reduced exercise. The purpose of this study is to understand the time-course of bone strength loss in space. We will use high resolution bone imaging to investigate how long it takes for bone loss to stabilize in space and whether stabilization differs between first-time and repeat flier astronauts. Results will help understand how to ensure astronauts remain healthier on longer-duration missions and the risks of very long spaceflights in the future.
Description (French)
Effet du vol spatial de longue durée sur la microarchitecture et la force osseuses en utilisant une imagerie tridimensionnelle à haute résolution. Nos os s'adaptent continuellement pour supporter le poids de notre corps dans un environnement de gravité. Les os s'affaiblissent lorsque le stress quotidien est réduit. Les astronautes perdent rapidement de la force dans les os lorsqu'ils sont dans l'espace en raison de l'apesanteur et de la diminution de l'exercice. Le but de cette étude est de comprendre l'évolution temporelle de la perte de résistance des os dans l'espace. Nous utiliserons l'imagerie osseuse à haute résolution pour déterminer le temps nécessaire pour que la perte osseuse se stabilise dans l'espace et pour déterminer si la stabilisation diffère entre les astronautes qui effectuent un premier vol ou qui effectuent de nouveaux vols. Les résultats aideront à comprendre comment assurer la santé des astronautes lors de missions de longue durée et les risques de très longs vols spatiaux à l'avenir.
Expected Results
The Research component of the program provides financial support to organizations to conduct space related research and development in priority areas. It will support targeted knowledge development and innovation to sustain and enhance the Canadian capacity to use space to address national needs and priorities in the future.
Expected Results (French)
Le volet Recherche du programme offre aux organisations une aide financière qui leur permettra de mener leurs activités de recherche et développement spatiales dans des secteurs prioritaires. Ce volet appuiera le développement des connaissances et l’innovation dans les domaines ciblés de manière à soutenir et à accroître la capacité du Canada d’utiliser l’espace pour répondre aux besoins et aux priorités du pays dans le futur.
Organization Code
csa-asc
Organization
Canadian Space Agency | Agence spatiale canadienne
Program Name
Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology
Program Name (French)
Programme global de subventions et contributions à l'appui de la recherche, de la sensibilisation et de l'éducation en sciences et technologies spatiales
Program Purpose
This program supports knowledge development and innovation in the CSA's priority areas while increasing the awareness and participation of Canadians in space-related disciplines and activities. The Research Component aims to support the development of science and technology; foster the continual development of a critical mass of researchers and highly qualified people in Canada; and support information gathering and space-related studies and research pertaining to Canadian Space Agency priorities.
Program Purpose (French)
Ce programme appuie le développement des connaissances et l'innovation dans des domaines prioritaires de l'ASC et accroît la sensibilisation et la participation des Canadiens aux disciplines et aux activités liées à l'espace. Le volet Recherche vise à soutenir le développement des sciences et des technologies, à favoriser le développement continu d'une masse critique de chercheurs et de personnes hautement qualifiées au Canada, et à appuyer la collecte d'information, la recherche et les études relatives à l'espace en tenant compte des priorités de l'ASC.
Recipient City
Calgary|Calgary
Recipient Country
CA
Recipient Legal Name
University of Calgary|University of Calgary
Recipient Operating Name
University of Calgary|Université de Calgary
Recipient Postal Code
T2N 4Z6
Recipient Province or Territory
AB
Recipient Type
S
Reference Number
003-2019-2020-Q2-04301