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Grant: Alliance Grants

University of Toronto

$376,500.00

BioMax: Oxidoreductases for hemicellulose upgrading to bio-derived cross-linkers

FY 2022-23

Summary
Emerging bio-based economies are valued in the hundreds of billion dollars and are seen as an opportunity for creating new jobs for rural communities close to renewable bioresources. However, products generated from renewable bioresources are not necessarily greener, and sustainable bio-based economies require efficiency of bioresource conversion and application. The overall mission of the BioMax project is to create breakthrough biotechnologies that sustainably upgrade biomass residuals to high-value products, creating new economic opportunities for Canadian biorefineries. The specific goal is to establish carbohydrate oxidoreductases for the conversion of underused hemicelluloses to cross-linking molecules, relevant to sustainable textile manufacturing. Over the next two-years, the project team of computational scientists, biochemists, bioprocess engineers and material scientists will deliver: 1) 20 new enzyme designs predicted to display improved activity towards diverse hemicelluloses, 2) improved industrial hosts for cost-effective production of the targeted oxidoreductases, and 3) enzyme systems that efficiently transform underused hemicelluloses to molecules that cross-link cellulosic fibre.By establishing biotechnologies that upgrade hemicelluloses and advance sustainable textile manufacturing, this project supports three key aims of the project partner: 1) integrate new enzyme technologies into Canadian forest biorefineries, 2) maximize the efficient use of bioresources by valorising underused hemicelluloses that make up ~25% of biomass feedstocks, and 3) expand opportunities for dissolving pulp mills in sustainable textile manufacturing.
Program
Alliance Grants
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data

As published

Application id
570676-2021
Name nom
Master, Emma ER
Department département
Chemical Engineering and Applied Chemistry
Organization id
31
Institution établissement
University of Toronto
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2022
Competition year année de concours
2021
Award amount
376500
Program id
ALLRP
Program name en
Alliance Grants
Program name fr
Subventions Alliance
Group en
RESEARCH PARTNERSHIPS
Group fr
PARTENARIATS DE RECHERCHE
Committee code
96
Committee name en
RPP Internal Decision Cttee
Committee name fr
Cté de décision interne - PPR
Area of application code
503
Area of application group en
Manufacturing processes and products
Area of application group fr
Procédés et produits industriels
Area of application en
Wood, wood products and paper
Area of application fr
Bois, produits du bois et papier
Research subject code
1802
Research subject group en
Chemical engineering
Research subject group fr
Génie chimique
Research subject en
Biochemical engineering
Research subject fr
Génie biochimique
Installment
inst:2;3
Partie
2
Nb partie
3
Application title
BioMax: Oxidoreductases for hemicellulose upgrading to bio-derived cross-linkers
Application summary
Emerging bio-based economies are valued in the hundreds of billion dollars and are seen as an opportunity for creating new jobs for rural communities close to renewable bioresources. However, products generated from renewable bioresources are not necessarily greener, and sustainable bio-based economies require efficiency of bioresource conversion and application. The overall mission of the BioMax project is to create breakthrough biotechnologies that sustainably upgrade biomass residuals to high-value products, creating new economic opportunities for Canadian biorefineries. The specific goal is to establish carbohydrate oxidoreductases for the conversion of underused hemicelluloses to cross-linking molecules, relevant to sustainable textile manufacturing. Over the next two-years, the project team of computational scientists, biochemists, bioprocess engineers and material scientists will deliver: 1) 20 new enzyme designs predicted to display improved activity towards diverse hemicelluloses, 2) improved industrial hosts for cost-effective production of the targeted oxidoreductases, and 3) enzyme systems that efficiently transform underused hemicelluloses to molecules that cross-link cellulosic fibre.By establishing biotechnologies that upgrade hemicelluloses and advance sustainable textile manufacturing, this project supports three key aims of the project partner: 1) integrate new enzyme technologies into Canadian forest biorefineries, 2) maximize the efficient use of bioresources by valorising underused hemicelluloses that make up ~25% of biomass feedstocks, and 3) expand opportunities for dissolving pulp mills in sustainable textile manufacturing.