Grant: Project Grant
McMaster University
$937,740.00
Utilizing chimeric antigen receptors to direct autologous NK cell cytotoxicity to breast cancer
FY 2017-18
Summary
Despite significant progress in the early detection and treatment of breast cancer, about 10-15% of newly diagnosed breast cancer patients do not respond well to currently available treatment options. New effective treatment options are urgently needed. While breast cancer suppress our immune system, we have recently learned how to post our immune system to fight cancer. Recent advances in cancer immunotherapy have provided much optimism due to the development of effective novel treatments for breast cancer, particularly for the ones we do not have effective treatment options. In this project we would like to develope new cancer immunotherapy using body's own cancer fighting cells Called: Natural killer cells.
Department
Program
Project Grant
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
380931
Name
Ashkar Ali A
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Cancer Biology & Therapeutics
Projecttitle
Utilizing chimeric antigen receptors to direct autologous NK cell cytotoxicity to breast cancer
Programtype2
Operating Grants
Orgnameinp2
McMaster University
Cihramount2
$937,740
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Breast Cancer; Cancer Immunotherapy; Car-Nk; Nk Cells
Abstract
Despite significant progress in the early detection and treatment of breast cancer, about 10-15% of newly diagnosed breast cancer patients do not respond well to currently available treatment options. New effective treatment options are urgently needed. While breast cancer suppress our immune system, we have recently learned how to post our immune system to fight cancer. Recent advances in cancer immunotherapy have provided much optimism due to the development of effective novel treatments for breast cancer, particularly for the ones we do not have effective treatment options. In this project we would like to develope new cancer immunotherapy using body's own cancer fighting cells Called: Natural killer cells.
Competitiondate
201803
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Ashkar, Ali A
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $937,740~ $0~
