Grant: Travel Awards - Institute Community Support
University of British Columbia
$2,644.00
Perinatal and early infant outcomes after bictegravir exposure in pregnancy: a Canadian surveillance study
FY 2025-26
Summary
Bictegravir (BIC) is a medication used to treat HIV, but until recently, there was limited information about its safety during pregnancy. Our study looked at pregnancy and infant outcomes among people who used BIC during pregnancy in Canada.
We analyzed data from over 1,200 pregnancies between 2018 and 2023, including 161 where BIC was used. People taking BIC were more likely to be Indigenous or have a history of injection drug use. Babies exposed to BIC were slightly more likely to be born early (preterm), but when we accounted for other factors that increase the risk of early birth, this difference was no longer significant.
Overall, we found no evidence that using BIC during pregnancy increases the risk of poor outcomes for the parent or baby. These results support current recommendations that BIC can be safely used during pregnancy.
Department
Program
Travel Awards - Institute Community Support
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
556312
Name
Wong Jeffrey Man Hay
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Infection and Immunity
Theme2
Clinical
Prcname2
Travel Awards - Institute Community Support
Projecttitle
Perinatal and early infant outcomes after bictegravir exposure in pregnancy: a Canadian surveillance study
Programtype2
Undefined
Orgnameinp2
University of British Columbia
Cihramount2
$2,644
Cihrequipment2
$0
Programname2
Travel Awards - Institute Community Support
Keyworddelim
Ics Travel Awards
Abstract
Bictegravir (BIC) is a medication used to treat HIV, but until recently, there was limited information about its safety during pregnancy. Our study looked at pregnancy and infant outcomes among people who used BIC during pregnancy in Canada.
We analyzed data from over 1,200 pregnancies between 2018 and 2023, including 161 where BIC was used. People taking BIC were more likely to be Indigenous or have a history of injection drug use. Babies exposed to BIC were slightly more likely to be born early (preterm), but when we accounted for other factors that increase the risk of early birth, this difference was no longer significant.
Overall, we found no evidence that using BIC during pregnancy increases the risk of poor outcomes for the parent or baby. These results support current recommendations that BIC can be safely used during pregnancy.
Competitiondate
202511
Approvedterm2
1 yr 0 mth
Pinamesdelim
Wong, Jeffrey Man Hay
Approvedterm
1 an 0 mois
Cihrcontribution2
MI #3~ $2,644~ $0~
