Grant: Collaborative Health Research Projects
Université de Sherbrooke
$90,800.00
Responses of bone cells to biomaterials
FY 2007-08
Summary
Canada will have 6.7 million senior citizens (over 65) in 2021 and 9.2 million in 2041, nearly 25%Canadians. Such an aging population is particularly prone to bone fractures, so that bone replacement willbecome an ever bigger and more costly problem.- The current standard for bone replacement is the autograft. However, harvesting an autograft requiresadditional surgery at the donor site that is related to high level of morbidity (25%). The quantities of bonetissue that can be harvested are limited.- Despite the benefits of autograft, its limitations have necessitated the pursuit of alternatives usingbiomaterials. However tridimensional biomimetic material are difficult to develop because little is knownconcerning the cooperation of bone cells in 3D biomaterials, and their response to specific molecules.- Our interdisciplinary team includes a biochemist, materials engineer, biomechanical engineer, biologist,rheumatologist and an orthopedic surgeon. Our team will developp new bone substitutes by determining how3D biomimetic composite biomaterials may influence the capacities of bone cells to function and respond totheir environment. Such new bone substitutes might reduce surgical complication and time patients spend inhospital.
Program
Collaborative Health Research Projects
Recipient
Location
Quebec, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
337881-2007
Name nom
Faucheux, Nathalie
Department département
Génie chimique
Organization id
68
Institution établissement
Université de Sherbrooke
Province en
Québec
Province fr
Québec
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2007
Competition year année de concours
2007
Award amount
90800
Program id
CHRPJ
Program name en
Collaborative Health Research Projects
Program name fr
Projets de recherche concertée sur la santé
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
360
Committee name en
Collaborative Health Research Projects Selection Panel
Committee name fr
Comité de sélection de projets de recherche concertée sur la santé
Area of application code
1102
Area of application group en
Health, education and social services
Area of application group fr
Santé publique, éducation et services sociaux
Area of application en
Biomedical engineering
Area of application fr
Génie biomédical
Research subject code
1800
Research subject group en
Chemical engineering
Research subject group fr
Génie chimique
Research subject en
Chemical engineering
Research subject fr
Génie chimique
Partie
1
Nb partie
3
Application title
Responses of bone cells to biomaterials
Keyword
NA
Application summary
Canada will have 6.7 million senior citizens (over 65) in 2021 and 9.2 million in 2041, nearly 25%Canadians. Such an aging population is particularly prone to bone fractures, so that bone replacement willbecome an ever bigger and more costly problem.- The current standard for bone replacement is the autograft. However, harvesting an autograft requiresadditional surgery at the donor site that is related to high level of morbidity (25%). The quantities of bonetissue that can be harvested are limited.- Despite the benefits of autograft, its limitations have necessitated the pursuit of alternatives usingbiomaterials. However tridimensional biomimetic material are difficult to develop because little is knownconcerning the cooperation of bone cells in 3D biomaterials, and their response to specific molecules.- Our interdisciplinary team includes a biochemist, materials engineer, biomechanical engineer, biologist,rheumatologist and an orthopedic surgeon. Our team will developp new bone substitutes by determining how3D biomimetic composite biomaterials may influence the capacities of bone cells to function and respond totheir environment. Such new bone substitutes might reduce surgical complication and time patients spend inhospital.
