Grant: Operating Grant: SickKids-CIHR-IHDCYH New Investigator Grants

Cannabis is the most common recreational and medicinal psychoactive drug used among women of reproductive age. It is often used, during pregnancy and lactation for various reasons including, nausea and vomiting, treating chronic pain, coping with anxiety and for sleep [1, 2]. Metabolites of cannabis are found in breast milk and can accumulate in higher concentrations with ongoing consumption, which is concerning for potential exposure among infants born to mothers who consume cannabis. It is currently unknown if maternal cannabis use influences breast milk composition or volume. There is evidence suggesting that changes in breast milk composition in general may alter infant growth and development [3]. The primary objective of this study is to investigate the impact of maternal cannabis use on macronutrient, micronutrient, and immune factors in breast milk. The secondary objective is to examine patterns of lactation and to explore barriers to ongoing breast feeding among women who choose to consume cannabis. It is paramount that we increase our understanding of the potential effects of maternal cannabis use on fetal and infant development so that families can be counselled using an evidence-based and patient-centered approach.