Grant: Planning and Dissemination Grant - Institute Community Support
Ottawa Hospital Research Institute
$10,000.00
Establishing a national consensus on humane endpoints for preclinical models of acute lung injury
FY 2014-15
Summary
Acute respiratory distress syndrome (ARDS) is a devastating clinical condition in the intensive care unit. It is usually caused by a serious infection and it results in death of up to 60% of people who develop it. There are currently limited treatments for this disease, and ongoing research is the only way to discover new treatments for ARDS. Using animals to perform research on ARDS is currently the best way to represent the complex processes that underlie it.
Many researchers across Canada use animal models of this disease in order to study it. One aspect that makes this research difficult is the lack of a standardized way to assess the sickness of individual animals with ARDS. Our group of scientists, physicians, and veterinarians would like to make a national, standardized way to assess how sick individual animals are. We believe that a consensus on how these assessments should be performed will allow scientists from different institutions to work with each other more easily, and also preserve animal life while minimizing animal distress. Ultimately, we believe this will lead to results from animal research being translated more readily to clinical therapies for patients with ARDS.
Department
Program
Planning and Dissemination Grant - Institute Community Support
Recipient
Location
Ontario, Canada
Recipient Type
Other
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
325198
Name
Stewart Duncan J
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Infection and Immunity
Theme2
Biomedical
Prcname2
Planning and Dissemination - III
Projecttitle
Establishing a national consensus on humane endpoints for preclinical models of acute lung injury
Programtype2
Miscellaneous Programs
Orgnameinp2
Ottawa Hospital Research Institute
Cihramount2
$10,000
Cihrequipment2
$0
Programname2
Planning and Dissemination Grant - Institute Community Support
Keyworddelim
Acute Lung Injury; Acute Respiratory Distress Syndrome; Animal Welfare; Consensus Meeting; Preclinical; Reporting Guidelines; Translational Science
Abstract
Acute respiratory distress syndrome (ARDS) is a devastating clinical condition in the intensive care unit. It is usually caused by a serious infection and it results in death of up to 60% of people who develop it. There are currently limited treatments for this disease, and ongoing research is the only way to discover new treatments for ARDS. Using animals to perform research on ARDS is currently the best way to represent the complex processes that underlie it.
Many researchers across Canada use animal models of this disease in order to study it. One aspect that makes this research difficult is the lack of a standardized way to assess the sickness of individual animals with ARDS. Our group of scientists, physicians, and veterinarians would like to make a national, standardized way to assess how sick individual animals are. We believe that a consensus on how these assessments should be performed will allow scientists from different institutions to work with each other more easily, and also preserve animal life while minimizing animal distress. Ultimately, we believe this will lead to results from animal research being translated more readily to clinical therapies for patients with ARDS.
Competitiondate
201502
Approvedterm2
1 yr 0 mth
Pinamesdelim
Stewart, Duncan J
Approvedterm
1 an 0 mois
Cihrcontribution2
Inst of Infection & Immunity~ $10,000~ $0~