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Grant: Canada Research Chairs

The University of British Columbia

$200,000.00

Animal Functional Genomics and Microbiome

FY 2024-25

Summary
The world is facing great challenges in food security in the next decades with the world’s population expected to reach nearly 10 billion and 60% more food needed by 2050. Beef and dairy farms are the key global agriculture sectors that provide animal proteins (meat and milk, accounting 45% of global animal protein) to meet the nutritional needs of humans. However, there are increasing concerns surrounding production inefficiency, agriculture’s environmental footprint (e.g., greenhouse gas (GHG) emission and manure), animal health and welfare, and one health (animal, human and environmental health such as zoonotic diseases and antimicrobial resistance transmissions). In Canada, cattle farming is the largest livestock industry, and continued improvements in production efficiency and health of cattle are central to ensuring sector sustainability and growth while minimizing its environmental footprint Therefore, novel technologies are needed for the cattle industry to improve production efficiency, environmental sustainability, health and welfare of Canada’s cattle population to adapt to consumer demands, changing regulatory requirements on environmental concerns and food product safety as well as the increasing prevalence of climate extremes. This is central to ensuring the sustainability and competitiveness of the cattle industry in Canada and globally. The proposed research will address the above new challenges through the following research areas based on functional genomics, microbial genomics, and multiomics (transcriptomics and metabolomics) for host-microbiome interactions: 1) Novel microbial genomics-based microbiome solutions for reducing methane emission and foodborne pathogen colonization in cattle; 2). Host-Microbiome driven interventions to improve animal health to reduce infectious diseases and antimicrobial usages; 3). Multi-omics to understand molecular basis of animal welfare and product quality in response to environmental and climate changes; 4). BigData and machine learning for precision farming and decision making to translate the omics research to precision management strategies to reduce GHG and improve production efficiency. Outcomes of these novel and innovative multidisciplinary and interdisciplinary research will lead to the microbiome and omics-based solutions for sustainable livestock production, climate adaption and mitigation technologies, improved animal productivity, health and welfare.
Program
Canada Research Chairs
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data

As published

Application id
CRC-2022-00062
Name nom
Guan, Leluo
Department département
Faculty of Land and Food Systems - The University of British Columbia
Organization id
2
Institution établissement
The University of British Columbia
Province en
British Columbia
Province fr
Colombie-Britannique
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2024
Competition year année de concours
2022
Award amount
200000
Program id
CRC
Program name en
Canada Research Chairs
Program name fr
Chaires de recherche du Canada
Group en
DISCOVERY RESEARCH
Group fr
RECHERCHE AXÉE SUR LA DÉCOUVERTE
Committee code
9998
Committee name en
Canada Research Chair Selection Committee
Committee name fr
Comité de sélection des Chaires de recherche du Canada
Area of application code
9999
Area of application group en
Not available
Area of application group fr
Non disponible
Area of application en
Not available
Area of application fr
Non disponible
Research subject code
9999
Research subject group en
Not available
Research subject group fr
Non disponible
Research subject en
Not available
Research subject fr
Non disponible
Field of research list codes
RDF1060607
Field of research list names en
Gene regulation and expression
Field of research list names fr
Régulation et expression des gènes
Socioeconomic objective list codes
RDS10806
Socioeconomic objective list names en
Livestock raising (including beekeeping and pet breeding)
Socioeconomic objective list names fr
Élevage du bétail (y compris l'apiculture et la reproduction des animaux de compagnie)
Application title
Animal Functional Genomics and Microbiome
Keywords
Microbiome; Host-microbiome interaction; Metagenomic and metatranscriptomics; Functional genomics; Livestock animals and products; non-coding RNAs; Feed efficiency; GHG mitigatioon; Food security and sustainability; multi-omics and system biology
Application summary
The world is facing great challenges in food security in the next decades with the world’s population expected to reach nearly 10 billion and 60% more food needed by 2050. Beef and dairy farms are the key global agriculture sectors that provide animal proteins (meat and milk, accounting 45% of global animal protein) to meet the nutritional needs of humans. However, there are increasing concerns surrounding production inefficiency, agriculture’s environmental footprint (e.g., greenhouse gas (GHG) emission and manure), animal health and welfare, and one health (animal, human and environmental health such as zoonotic diseases and antimicrobial resistance transmissions). In Canada, cattle farming is the largest livestock industry, and continued improvements in production efficiency and health of cattle are central to ensuring sector sustainability and growth while minimizing its environmental footprint Therefore, novel technologies are needed for the cattle industry to improve production efficiency, environmental sustainability, health and welfare of Canada’s cattle population to adapt to consumer demands, changing regulatory requirements on environmental concerns and food product safety as well as the increasing prevalence of climate extremes. This is central to ensuring the sustainability and competitiveness of the cattle industry in Canada and globally. The proposed research will address the above new challenges through the following research areas based on functional genomics, microbial genomics, and multiomics (transcriptomics and metabolomics) for host-microbiome interactions: 1) Novel microbial genomics-based microbiome solutions for reducing methane emission and foodborne pathogen colonization in cattle; 2). Host-Microbiome driven interventions to improve animal health to reduce infectious diseases and antimicrobial usages; 3). Multi-omics to understand molecular basis of animal welfare and product quality in response to environmental and climate changes; 4). BigData and machine learning for precision farming and decision making to translate the omics research to precision management strategies to reduce GHG and improve production efficiency. Outcomes of these novel and innovative multidisciplinary and interdisciplinary research will lead to the microbiome and omics-based solutions for sustainable livestock production, climate adaption and mitigation technologies, improved animal productivity, health and welfare.
The University of British Columbia - $200,000 Grant (… | Canada Spends