Grant: CIHR - ICR / Cancer Research Society Partnership - Research Grants
York University (Toronto, Ontario)
$65,000.00
Site-specific oxidation of guanine for studying cancer epigenetics
FY 2023-24
Summary
The genome serves as the blueprint for life, functioning as an instruction manual that orchestrates the behaviour of each living organism. Cancer cells modify their DNA to enhance their ability to proliferate. Understanding how cancer cells utilize DNA modifications for their survival is critical for developing new cancer therapeutics. To achieve this, we propose to develop a molecular machine capable of introducing specific DNA modifications inside living cells. Achieving our objectives will result in an increased understanding of cancer biology. This will be highly useful for developing new cancer therapeutics or potentiating existing therapies for Canadians suffering from cancer.
Department
Program
CIHR - ICR / Cancer Research Society Partnership - Research Grants
Recipient
Location
Ontario, Canada
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
511006
Name
Kim Sebastian B
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Partnername
Cancer Research Society Inc.; Cancer Research Society Inc.
Instname2
Cancer Research
Prcname2
Special Cases
Projecttitle
Site-specific oxidation of guanine for studying cancer epigenetics
Programtype2
Operating Grants
Orgnameinp2
York University (Toronto, Ontario)
Cihramount2
$65,000
Cihrequipment2
$0
Programname2
CIHR - ICR / Cancer Research Society Partnership - Research Grants
Keyworddelim
Early Career Researchers
Abstract
The genome serves as the blueprint for life, functioning as an instruction manual that orchestrates the behaviour of each living organism. Cancer cells modify their DNA to enhance their ability to proliferate. Understanding how cancer cells utilize DNA modifications for their survival is critical for developing new cancer therapeutics. To achieve this, we propose to develop a molecular machine capable of introducing specific DNA modifications inside living cells. Achieving our objectives will result in an increased understanding of cancer biology. This will be highly useful for developing new cancer therapeutics or potentiating existing therapies for Canadians suffering from cancer.
Competitiondate
202402
Approvedterm2
2 yrs 0 mth
Pinamesdelim
Kim, Sebastian B
Approvedterm
2 ans 0 mois
Cihrcontribution2
ICR~ $65,000~ $0~
