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Grant: Operating Grant: SPOR Innovative Clinical Trial Multi-Year Grant

Unity Health Toronto

$867,349.00

CoMFORT (Cow's Milk Fat Obesity pRevention Trial)

FY 2017-18

Summary
Childhood obesity is a looming healthcare crisis with 1 in 3 Canadian children now living with overweight or obesity. The long term consequences of childhood obesity include increased risk of cardiovascular disease, diabetes and stroke which reduce quality of life and longevity. Cardiovascular disease currently costs Canada's health systems $7 billion annually and is forecasted to triple in the next 30 years. Since 1992 Health Canada has recommended that children older than 2 years consume reduced fat milk (i.e. 1% milk fat) rather than whole milk (3.25% milk fat) to prevent childhood obesity. Unfortunately, childhood obesity has tripled since then and whole cow's milk intake has halved leading many to wonder whether the reduction in whole milk consumption is leading to childhood obesity. New research from our group and others supports that reduced milk fat intake early in life may be promoting rather than preventing childhood obesity. Although several biological mechanisms have been proposed, the leading theory is that children may feel more 'full' after consuming whole milk and less likely to seek calories from unhealthy foods. This innovative clinical trial will compare the effect of primary healthcare recommendation for whole milk (intervention) vs. reduced fat milk (control) in early childhood in optimizing childhood growth development and nutrition at 4-5 years of age. We will use new cohort trial methods leveraging Canada's largest childhood cohort study (TARGet Kids!) to conduct this trial which will minimize cost and maximize feasibility. This trial must be conducted now to ensure that primary healthcare providers are delivering the correct nutritional recommendation and to protect the next generation of Canada's children from the long term consequences of childhood obesity.
Program
Operating Grant: SPOR Innovative Clinical Trial Multi-Year Grant
Location
Ontario, Canada
Recipient Type
Other
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
379252
Name
Maguire Jonathon L
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Partnername
Applied Health Research Centre (Toronto, Ontario); Hospital for Sick Children (Toronto); Hospital for Sick Children (Toronto); Unity Health Toronto; McGill University Health Centre; McGill University Health Centre; Joannah and Brian Lawson Centre for Child Nutrition (Toronto, ON); Joannah and Brian Lawson Centre for Child Nutrition (Toronto, ON); Maternal Infant Child and Youth Research Network (Vancouver, BC); Public Health Ontario (Toronto); Offord Centre for Child Studies (Hamilton, ON); Quebec SPOR SUPPORT Unit (Longueuil, QC)
Instname2
Nutrition, Metabolism and Diabetes
Theme2
Clinical
Prcname2
Operating Grant: SPOR Innovative Clinical Trial Multi-Year Grant
Projecttitle
CoMFORT (Cow's Milk Fat Obesity pRevention Trial)
Programtype2
Operating Grants
Orgnameinp2
Unity Health Toronto
Cihramount2
$867,349
Cihrequipment2
$0
Programname2
Operating Grant: SPOR Innovative Clinical Trial Multi-Year Grant
Keyworddelim
Epidemiology; Nutrition; Obesity; Pediatrics; Vitamin D
Abstract
Childhood obesity is a looming healthcare crisis with 1 in 3 Canadian children now living with overweight or obesity. The long term consequences of childhood obesity include increased risk of cardiovascular disease, diabetes and stroke which reduce quality of life and longevity. Cardiovascular disease currently costs Canada's health systems $7 billion annually and is forecasted to triple in the next 30 years. Since 1992 Health Canada has recommended that children older than 2 years consume reduced fat milk (i.e. 1% milk fat) rather than whole milk (3.25% milk fat) to prevent childhood obesity. Unfortunately, childhood obesity has tripled since then and whole cow's milk intake has halved leading many to wonder whether the reduction in whole milk consumption is leading to childhood obesity. New research from our group and others supports that reduced milk fat intake early in life may be promoting rather than preventing childhood obesity. Although several biological mechanisms have been proposed, the leading theory is that children may feel more 'full' after consuming whole milk and less likely to seek calories from unhealthy foods. This innovative clinical trial will compare the effect of primary healthcare recommendation for whole milk (intervention) vs. reduced fat milk (control) in early childhood in optimizing childhood growth development and nutrition at 4-5 years of age. We will use new cohort trial methods leveraging Canada's largest childhood cohort study (TARGet Kids!) to conduct this trial which will minimize cost and maximize feasibility. This trial must be conducted now to ensure that primary healthcare providers are delivering the correct nutritional recommendation and to protect the next generation of Canada's children from the long term consequences of childhood obesity.
Competitiondate
201801
Approvedterm2
4 yrs 0 mth
Pinamesdelim
Maguire, Jonathon L; Manson, Heather; Tavares, Erika S; Weir-Seeley, Shannon; Birken, Catherine S; Li, Patricia T; Wong, Peter D
Approvedterm
4 ans 0 mois
Cihrcontribution2
Patient Oriented Research~ $867,349~ $0~
Unity Health Toronto - $867,349 Grant (2017-18) | Canada Spends