Grant: Operating Grant
Queen's University (Kingston, Ontario)
$737,535.00
Regulation of mast cell activation and inflammation
FY 2009-10
Summary
Mast cells are part of our immune system that can protect us from some infections. However, mast cells can also contribute to allergic diseases and promote tumour growth. In this proposal we investigate several important proteins that can regulate the accumulation of mast cells and the amounts of inflammatory mediators they release. Our goal is to identify new therapeutic targets to treat mast cell-related diseases.
Department
Program
Operating Grant
Location
Ontario, Canada
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
188978
Name
Craig Andrew W
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Infection and Immunity
Theme2
Biomedical
Prcname2
Immunology & Transplantation
Projecttitle
Regulation of mast cell activation and inflammation
Programtype2
Operating Grants
Orgnameinp2
Queen's University (Kingston, Ontario)
Cihramount2
$737,535
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Immunity; Inflammation; Mast Cells; Protein Kinases And Phosphorylation; Signal Transduction; Transgenic Mice
Abstract
Mast cells are part of our immune system that can protect us from some infections. However, mast cells can also contribute to allergic diseases and promote tumour growth. In this proposal we investigate several important proteins that can regulate the accumulation of mast cells and the amounts of inflammatory mediators they release. Our goal is to identify new therapeutic targets to treat mast cell-related diseases.
Competitiondate
200909
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Craig, Andrew W
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $737,535~ $0~
