Contribution: Industrial Research Assistance Program
Ripple Therapeutics Corporation
$150,000.00
Dry AMD manufacturing development and optimization
FY 2026-27 · 2026-04-01
Summary
Ripple Therapeutics Corporation is a clinical stage, privately held company that is focused on ophthalmic therapeutics with controllable, sustainable drug delivery. The Ripple pipeline currently has a number of drug conjugates under development targeting key ocular indications including dry age-related macular degeneration (dry AMD). AMD is the leading cause of vision loss in people over the age of 55, affecting approximately 2.5 million Canadians. It is estimated that up to 90% of AMD cases are dry AMD, and there are no therapeutic treatment options for dry AMD. Scientific and engineering resources will perform work on the manufacturability of Ripple’s complement factor B conjugates (RTC-CFBs) for the treatment of dry AMD.
Department
Program
Industrial Research Assistance Program
Recipient
Location
Toronto|Toronto, Ontario, Canada
Recipient Type
For-profit organization
Business Number
760459073
Type
Contribution
Source
Proactive Disclosure - Grants and Contributions
As published
Agreement End Date
2027-01-31
Agreement Number
1041947
Agreement Start Date
2026-04-01
Agreement Title
Dry AMD manufacturing development and optimization
Agreement Title (French)
Développement et optimisation de la fabrication de l’AMD sec
Agreement Type
Contribution
Agreement Value
$150,000.00
Amendment Number
0
Coverage
Industrial Research Assistance Program projects stimulate wealth creation for Canada through technological innovation and strengthen Canadian innovation ecosystem by creating new industrial capacity. | Les projets du Programme d'aide à la recherche industrielle favorisent la création de richesse au Canada grâce à l'innovation technologique et renforcent l'écosystème canadien de l'innovation en créant de nouvelles capacités industrielles.
Description
Ripple Therapeutics Corporation is a clinical stage, privately held company that is focused on ophthalmic therapeutics with controllable, sustainable drug delivery. The Ripple pipeline currently has a number of drug conjugates under development targeting key ocular indications including dry age-related macular degeneration (dry AMD). AMD is the leading cause of vision loss in people over the age of 55, affecting approximately 2.5 million Canadians. It is estimated that up to 90% of AMD cases are dry AMD, and there are no therapeutic treatment options for dry AMD. Scientific and engineering resources will perform work on the manufacturability of Ripple’s complement factor B conjugates (RTC-CFBs) for the treatment of dry AMD.
Description (French)
Ripple Therapeutics Corporation est une société privée au stade clinique qui se consacre aux traitements ophtalmologiques reposant sur un système d’administration de médicaments contrôlable et durable. Le portefeuille de produits de Ripple comprend actuellement plusieurs conjugués médicamenteux en cours de développement, ciblant des indications ophtalmologiques clés, notamment la dégénérescence maculaire liée à l’âge de type sec (DMLA sèche). La DMLA est la principale cause de perte de vision chez les personnes âgées de plus de 55 ans ; elle touche environ 2,5 millions de Canadiens. On estime que jusqu’à 90 % des cas de DMLA sont des cas de DMLA sèche, pour laquelle il n’existe actuellement aucune option thérapeutique. Des équipes scientifiques et d’ingénierie mèneront des travaux sur la faisabilité de la fabrication des conjugués au facteur B du complément (RTC-CFB) de Ripple destinés au traitement de la DMLA sèche.
Expected Results
The expected results and outcomes of NRC Industrial Research Assistance Program is focused on growing small and medium-sized enterprises (SMEs) through innovation and wealth creation for Canada.
Expected Results (French)
Les résultats attendus du Programme d’aide à la recherche industrielle du CNRC sont axés sur la croissance des petites et moyennes entreprises (PME) grâce à l’innovation et à la création de richesse pour le Canada.
Federal Riding
University--Rosedale
Federal Riding (French)
University--Rosedale
Federal Riding Number
35110
NAICS Code
32541
Organization Code
nrc-cnrc
Organization
National Research Council Canada | Conseil national de recherches Canada
Program Name
Industrial Research Assistance Program
Program Name (French)
Programme d’aide à la recherche industrielle
Program Purpose
The purpose of Industrial Research Assistance Program Contributions to Firms is to provide support that assists small and medium-sized enterprises (SMEs) to advance their innovation knowledge and ability to innovate, grow through innovation and stimulate wealth creation for Canada.
Program Purpose (French)
Les contributions versées aux entreprises en vertu du Programme d’aide à la recherche industrielle ont pour objectif d’apporter un soutien aux petites et moyennes entreprises (PME) afin qu’elles puissent approfondir leurs connaissances en matière d’innovation et renforcer leur capacité d’innovation, de croissance et de création de richesse pour le Canada.
Recipient Business Number
760459073
Recipient City
Toronto|Toronto
Recipient Country
CA
Recipient Legal Name
Ripple Therapeutics Corporation
Recipient Operating Name
Ripple Therapeutics
Recipient Postal Code
M5G 1L7
Recipient Province or Territory
ON
Recipient Type
F
Reference Number
172-2026-2027-Q1-1041947