Contribution: Industrial Research Assistance Program – Contributions to Firms
Oceans Limited
$58,652.00
Evaluate the Efficacy of a Novel Molecule Metabolite against Cancer
FY 2020-21 · 2020-11-23
Summary
Ocean Ltd. has successfully isolated and synthesized a novel molecule from seaweed harvested in NL waters that inhibits the growth of cancer cells. The proposed study will validate the efficacy of this molecule's open-ring metabolites and investigate the hypothesis that its open-ring ester hydrolysis form contributes to, or is responsible for, bioactivity by employing in vitro bioassays to confirm the metabolites bioactivity.
Oceans Ltd.'s discovery needs to be fully investigated and patent protected in case the biological activity of the parent compound is mediated in whole or in part by the metabolite form. Therefore, more in vitro data is required to ensure the firm's patent is expanded wide enough to cover both eventualities if the data indicates that is necessary.
Department
Program
Industrial Research Assistance Program – Contributions to FirmsIndustrial Research Assistance Program-Contributions to Firms (linked with high confidence)
Recipient
Location
St. John's|St. John's, Newfoundland and Labrador, Canada
Recipient Type
For-profit organization
Business Number
103971404
Type
Contribution
Source
Proactive Disclosure - Grants and Contributions
As published
Agreement End Date
2021-12-31
Agreement Number
960828
Agreement Start Date
2020-11-23
Agreement Title
Evaluate the Efficacy of a Novel Molecule Metabolite against Cancer
Agreement Title (French)
Évaluer l'efficacité d'un nouveau métabolite moléculaire contre le cancer
Agreement Type
Contribution
Agreement Value
$58,652.00
Amendment Number
0
Coverage
IRAP Contributions to Firms projects stimulate wealth creation for Canada through technological innovation. | Les projets des Contributions aux entreprises stimulent la création de richesse au Canada grâce à l’innovation technologique.
Description
Ocean Ltd. has successfully isolated and synthesized a novel molecule from seaweed harvested in NL waters that inhibits the growth of cancer cells. The proposed study will validate the efficacy of this molecule's open-ring metabolites and investigate the hypothesis that its open-ring ester hydrolysis form contributes to, or is responsible for, bioactivity by employing in vitro bioassays to confirm the metabolites bioactivity.
Oceans Ltd.'s discovery needs to be fully investigated and patent protected in case the biological activity of the parent compound is mediated in whole or in part by the metabolite form. Therefore, more in vitro data is required to ensure the firm's patent is expanded wide enough to cover both eventualities if the data indicates that is necessary.
Description (French)
Ocean Ltd. a réussi à isoler et à synthétiser une nouvelle molécule à partir d'algues marines récoltées dans les eaux néerlandaises qui inhibe la croissance des cellules cancéreuses. L'étude proposée permettra de valider l'efficacité des métabolites à cycle ouvert de cette molécule et d'étudier l'hypothèse selon laquelle sa forme d'hydrolyse ester à cycle ouvert contribue à la bioactivité ou en est responsable, en recourant à des essais biologiques in vitro pour confirmer la bioactivité des métabolites. La découverte d'Oceans Ltd. doit faire l'objet d'une étude approfondie et être protégée par un brevet au cas où l'activité biologique du composé d'origine serait en partie ou totalement modifiée par la forme du métabolite. Par conséquent, davantage de données in vitro sont nécessaires pour garantir que le brevet de l'entreprise soit suffisamment étendu pour couvrir les deux éventualités si les données indiquent que cela est nécessaire.
Expected Results
The purpose of IRAP Contributions to Firms is to support research, development, adoption and/or adaptation of innovative or technology-driven new or improved products, services or processes in Canada up to their commercialization
Expected Results (French)
Le PARI, par le biais des Contributions aux entreprises, vise à appuyer la recherche, le développement, l’adaptation et/ou l’adoption au Canada de produits, de services ou de processus novateurs ou axés sur des technologies nouvelles ou améliorées, et ce jusqu’à leur commercialisation
Federal Riding
St. John's South--Mount Pearl
Federal Riding (French)
St. John's-Sud--Mount Pearl
Federal Riding Number
10007
NAICS Code
541620
Organization Code
nrc-cnrc
Organization
National Research Council Canada | Conseil national de recherches Canada
Program Name
Industrial Research Assistance Program – Contributions to Firms
Program Name (French)
Programme d’aide à la recherche industrielle – Contributions aux entreprises
Program Purpose
The purpose of IRAP Contributions to Firms is to support research, development, adoption and/or adaptation of innovative or technology-driven new or improved products, services or processes in Canada up to their commercialization
Program Purpose (French)
Le PARI, par le biais des Contributions aux entreprises, vise à appuyer la recherche, le développement, l’adaptation et/ou l’adoption au Canada de produits, de services ou de processus novateurs ou axés sur des technologies nouvelles ou améliorées, et ce jusqu’à leur commercialisation
Recipient Business Number
103971404
Recipient City
St. John's|St. John's
Recipient Country
CA
Recipient Legal Name
Oceans Limited
Recipient Postal Code
A1C 2H1
Recipient Province or Territory
NL
Recipient Type
F
Reference Number
172-2020-2021-Q3-960828
