Grant: Operating Grant
University of Toronto
$514,560.00
Mitochondrial delivery of DNA-alkylating anticancer agents
EF 2011-12
Résumé
We are developing compounds that evade the resistance mechanisms that cancer cells use to override the effects of anticancer therapies. By delivering the drug to a unique site within the cell, therapeutic molecules are hidden from deactivators and made more potent and effective against resistant cancers.
Programme
Operating Grant
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
238344
Name
Kelley Shana O
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Cancer Progression & Therapeutics
Projecttitle
Mitochondrial delivery of DNA-alkylating anticancer agents
Programtype2
Operating Grants
Orgnameinp2
University of Toronto
Cihramount2
$514,560
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Anticancer Agents; Dna Alkylating Agents; Mitochondrial Drug Delivery; Peptides
Abstract
We are developing compounds that evade the resistance mechanisms that cancer cells use to override the effects of anticancer therapies. By delivering the drug to a unique site within the cell, therapeutic molecules are hidden from deactivators and made more potent and effective against resistant cancers.
Competitiondate
201109
Approvedterm2
4 yrs 0 mth
Pinamesdelim
Kelley, Shana O
Approvedterm
4 ans 0 mois
Cihrcontribution2
~ $514,560~ $0~
