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Grant: Project Grant

McGill University

$898,875.00

Neuronal basis of spatial cognition

EF 2017-18

Résumé
Our perception, thoughts and memory emerge from the collective activity of neuronal assemblies in large­scale brain networks, and unraveling the mechanisms underlying the communication between neuronal populations in various brain regions has become one of the central questions in neuroscience. My overarching goal is to understand how the brain processes sensory signals to generate spatial representations and memories that enable successful navigation. This research proposal aims to investigate how neuronal networks in vivo process the sense of head­direction, a critical piece of information for animals' navigation capabilities, how this signal is transformed into higher-level representation of space and how it participates to the formation of new spatial memories. Unraveling the relationship between, even basic, cognitive processes and neuronal dynamics will take us one step further toward understanding the neural basis of psychiatric disorders such as schizophrenia and other neurological disorders.
Programme
Project Grant
Bénéficiaire
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
371620
Name
Peyrache Adrien
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Neurosciences, Mental Health and Addiction
Theme2
Biomedical
Prcname2
Systems & Clinical Neurosciences - C
Projecttitle
Neuronal basis of spatial cognition
Programtype2
Operating Grants
Orgnameinp2
McGill University
Cihramount2
$898,875
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Cognition; Neuronal Circuits; Neuronal Dynamics; Optogenetics; Sensory Integration; Spatial Navigation
Abstract
Our perception, thoughts and memory emerge from the collective activity of neuronal assemblies in large­scale brain networks, and unraveling the mechanisms underlying the communication between neuronal populations in various brain regions has become one of the central questions in neuroscience. My overarching goal is to understand how the brain processes sensory signals to generate spatial representations and memories that enable successful navigation. This research proposal aims to investigate how neuronal networks in vivo process the sense of head­direction, a critical piece of information for animals' navigation capabilities, how this signal is transformed into higher-level representation of space and how it participates to the formation of new spatial memories. Unraveling the relationship between, even basic, cognitive processes and neuronal dynamics will take us one step further toward understanding the neural basis of psychiatric disorders such as schizophrenia and other neurological disorders.
Competitiondate
201709
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Peyrache, Adrien
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $898,875~ $0~