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Grant: CIHR-ICRH Travel Awards - ICRH / Vascular pool

University of Calgary

$1,500.00

DETERMINANTS OF OUTCOME TO DISEASE-MODIFYING THERAPY FOR TRANSTHYRETIN AMYLOIDOSIS CARDIOMYOPATHY

EF 2023-24

Résumé
Transthyretin amyloidosis cardiomyopathy is a disease that affects the heart tissue caused by the accumulation of abnormal proteins called amyloid plaques. Despite the approval of tafamidis, a stabilizer therapy, significant knowledge gaps exist regarding its use due to strict eligibility criteria and high costs. This study identified parameters that could be used in the predicting adverse outcomes of all-cause and cardiovascular mortality and hospitalization, as well as the associations of these predictors to tafamidis therapy. Various measures of baseline function were found to be associated with outcome and therapy.
Programme
CIHR-ICRH Travel Awards - ICRH / Vascular pool
Bénéficiaire
Emplacement
Alberta, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
495435
Name
Shahi Karan
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Prcname2
Special Cases
Projecttitle
DETERMINANTS OF OUTCOME TO DISEASE-MODIFYING THERAPY FOR TRANSTHYRETIN AMYLOIDOSIS CARDIOMYOPATHY
Programtype2
Undefined
Orgnameinp2
University of Calgary
Cihramount2
$1,500
Cihrequipment2
$0
Programname2
CIHR-ICRH Travel Awards - ICRH / Vascular pool
Keyworddelim
Outcomes; Transthyretin Amyloidosis Cardiomyopathy
Abstract
Transthyretin amyloidosis cardiomyopathy is a disease that affects the heart tissue caused by the accumulation of abnormal proteins called amyloid plaques. Despite the approval of tafamidis, a stabilizer therapy, significant knowledge gaps exist regarding its use due to strict eligibility criteria and high costs. This study identified parameters that could be used in the predicting adverse outcomes of all-cause and cardiovascular mortality and hospitalization, as well as the associations of these predictors to tafamidis therapy. Various measures of baseline function were found to be associated with outcome and therapy.
Competitiondate
202309
Approvedterm2
1 yr 0 mth
Pinamesdelim
Shahi, Karan
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $1,500~ $0~