Grant: Project Grant
Sunnybrook Research Institute (Toronto, Ontario)
$619,650.00
Objective Measures of Real-World Cochlear Implant Outcome Using Psychoacoustics and Electrophysiology
EF 2022-23
Résumé
In Canada, an estimated 7 million people suffer from debilitating hearing loss. Consequences of hearing loss are far-reaching and include high rates of social isolation, depression, and more recently has been identified as the greatest modifiable risk factor for dementia. Fortunately, with the advent of the cochlear implant (CI), people with severe hearing loss can have their hearing restored to some degree. A CI is a surgically implanted device that provides electrical stimulation of the auditory nerve feeding the auditory centres of the brain. It significantly enhances hearing, though there is substantial variability in speech perception and quality of life outcome. The underlying causes of this variability are not well understood. It has become clear that how we typically measure "outcome" is not optimal. For example, standard clinical measures that test abilities to detect simple sounds at the doctor's office often have little predictive value of how the CI improves speech perception in everyday life. The overall goal of this project is to develop and test new behavioural and neurophysiological methods using a realistic and ecologically valid framework. We believe that the use of realistic listening conditions will yield strong relationships with everyday accounts. We will use behavioural methods that quantify one's ability to separate different talkers and to remember what was said. We will use recently developed methods to quantify how well the brain can "track" different speech streams mimicking how we follow natural conversations. These novel findings can lead to more precise and patient-based rehabilitation in people with hearing loss and provide metrics when assessing those who may be at risk for developing dementia.
Programme
Project Grant
Bénéficiaire
Emplacement
Ontario, Canada
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
469039
Name
Dimitrijevic Andrew
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Neurosciences, Mental Health and Addiction
Theme2
Clinical
Prcname2
Behavioural Sciences - B-2
Projecttitle
Objective Measures of Real-World Cochlear Implant Outcome Using Psychoacoustics and Electrophysiology
Programtype2
Operating Grants
Orgnameinp2
Sunnybrook Research Institute (Toronto, Ontario)
Cihramount2
$619,650
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Biomakers; Cochlear Implants; Hearing; Quality Of Life; Speech Perception
Abstract
In Canada, an estimated 7 million people suffer from debilitating hearing loss. Consequences of hearing loss are far-reaching and include high rates of social isolation, depression, and more recently has been identified as the greatest modifiable risk factor for dementia. Fortunately, with the advent of the cochlear implant (CI), people with severe hearing loss can have their hearing restored to some degree. A CI is a surgically implanted device that provides electrical stimulation of the auditory nerve feeding the auditory centres of the brain. It significantly enhances hearing, though there is substantial variability in speech perception and quality of life outcome. The underlying causes of this variability are not well understood. It has become clear that how we typically measure "outcome" is not optimal. For example, standard clinical measures that test abilities to detect simple sounds at the doctor's office often have little predictive value of how the CI improves speech perception in everyday life. The overall goal of this project is to develop and test new behavioural and neurophysiological methods using a realistic and ecologically valid framework. We believe that the use of realistic listening conditions will yield strong relationships with everyday accounts. We will use behavioural methods that quantify one's ability to separate different talkers and to remember what was said. We will use recently developed methods to quantify how well the brain can "track" different speech streams mimicking how we follow natural conversations. These novel findings can lead to more precise and patient-based rehabilitation in people with hearing loss and provide metrics when assessing those who may be at risk for developing dementia.
Competitiondate
202209
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Dimitrijevic, Andrew
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $619,650~ $0~