Grant: Collaborative Health Research Projects (NSERC partnered)
Polytechnique Montréal
$252,318.00
Endovascular navigation of magnetic drug eluting beads for liver cancer therapy: Feasibility and optimization
EF 2014-15
Résumé
HepatoCellular Carcinoma (HCC) (liver cancer) is the fifth most common cancer in the world and third cause of cancer
mortality and its incidence is increasing worldwide and intra-arterial therapies are now the preferred therapeutic approach for
advanced HCC. Unlike other existing interventional methods, we propose a non-invasive treatment concept which consists
in injecting special drug-carrying biodegradable magnetic carriers being navigated directly to the site being treated using a
clinical Magnetic Resonance Imaging (MRI) scanner in order to enhance the treatment of liver cancer. We have previously
proven its feasibility in a rabbit model. However, the technology must first be adapted to the human scale before considering
clinical translation, which is the main goal of this project.
Programme
Collaborative Health Research Projects (NSERC partnered)
Bénéficiaire
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
316837
Name
Martel Sylvain
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Partnername
Natural Sciences and Engineering Research Council of Canada (NSERC)
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Collaborative Health Research Projects - NSERC Partnered
Projecttitle
Endovascular navigation of magnetic drug eluting beads for liver cancer therapy: Feasibility and optimization
Programtype2
Operating Grants
Orgnameinp2
Polytechnique Montréal
Cihramount2
$252,318
Cihrequipment2
$0
Programname2
Collaborative Health Research Projects (NSERC partnered)
Keyworddelim
Chemo-Embolization; Embolization; Hepatocellular Carcinoma (Hcc); Interventional Radiology; Liver Cancer; Magnetic Drug Eluting Beads (Mdeb); Magnetic Resonance Imaging (Mri); Mri-Based Endovascular Navigation
Abstract
HepatoCellular Carcinoma (HCC) (liver cancer) is the fifth most common cancer in the world and third cause of cancer
mortality and its incidence is increasing worldwide and intra-arterial therapies are now the preferred therapeutic approach for
advanced HCC. Unlike other existing interventional methods, we propose a non-invasive treatment concept which consists
in injecting special drug-carrying biodegradable magnetic carriers being navigated directly to the site being treated using a
clinical Magnetic Resonance Imaging (MRI) scanner in order to enhance the treatment of liver cancer. We have previously
proven its feasibility in a rabbit model. However, the technology must first be adapted to the human scale before considering
clinical translation, which is the main goal of this project.
Competitiondate
201410
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Martel, Sylvain; Soulez, Gilles
Approvedterm
3 ans 0 mois
Cihrcontribution2
Major Initiatives #2~ $252,318~ $0~
