Grant: Operating Grant
University of Alberta
$665,800.00
Novel protective roles for ATP-sensitive potassium channels in the heart
EF 2012-13
Résumé
Heart attacks are a major cause of death and disability in Canada. The proposed research will
help determine how cellular pathways in the heart may be harnessed in the clinic to reduce the damage sustained to the heart during a heart attack. Furthermore, we will investigate whether commonly used anti-diabetic drugs may actually contribute to heart damage in people with diabetes taking these medications. It is the overall aim of this research to increase the quality of life of Canadians after a heart attack and reduce the economic burden of caring for patients who develop chronic heart disease after a heart attack.
Programme
Operating Grant
Bénéficiaire
Emplacement
Alberta, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
265749
Name
Light Peter E
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Circulatory and Respiratory Health
Theme2
Biomedical
Prcname2
Cardiovascular System - A: Cells and Tissues
Projecttitle
Novel protective roles for ATP-sensitive potassium channels in the heart
Programtype2
Operating Grants
Orgnameinp2
University of Alberta
Cihramount2
$665,800
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Amp Activated Kinase; Atp-Sensitive Potassium Channel; Cardioprotection; Electrophysiology; Ion Channels; Ionic Homeostasis; Ischemia Reperfusion Injury; Patch-Clamp
Abstract
Heart attacks are a major cause of death and disability in Canada. The proposed research will
help determine how cellular pathways in the heart may be harnessed in the clinic to reduce the damage sustained to the heart during a heart attack. Furthermore, we will investigate whether commonly used anti-diabetic drugs may actually contribute to heart damage in people with diabetes taking these medications. It is the overall aim of this research to increase the quality of life of Canadians after a heart attack and reduce the economic burden of caring for patients who develop chronic heart disease after a heart attack.
Competitiondate
201209
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Light, Peter E
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $665,800~ $0~
