Grant: CIHR - ICR / Cancer Research Society Partnership - Res. Grants - Breast Cancer
Queen's University (Kingston, Ontario)
$60,000.00
Characterization of PTPN12 as a novel regulator of the Hippo pathway in breast cancer metastasis
EF 2021-22
Résumé
Breast cancer is the most frequently diagnosed cancer in women, killing about 680,000 people worldwide each year. Of all these women, over 90% of them die of tumor metastasis, a process in which tumors spread from the breast to other parts of the body such as lung and bone. However, treatment for metastatic breast cancer is not effective because we do not fully understand how cancer cells spread. In this research project, we will explore how a gene called PTPN12 regulates a group of genes called “Hippo” in controlling breast cancer spreading. Our studies will have great implication for the successful treatment of metastasized breast cancer in the future.
Programme
CIHR - ICR / Cancer Research Society Partnership - Res. Grants - Breast Cancer
Bénéficiaire
Emplacement
Ontario, Canada
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
468137
Name
Yang Xiaolong
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Partnername
Cancer Research Society Inc.; Cancer Research Society Inc.
Instname2
Cancer Research
Prcname2
Special Cases
Projecttitle
Characterization of PTPN12 as a novel regulator of the Hippo pathway in breast cancer metastasis
Programtype2
Operating Grants
Orgnameinp2
Queen's University (Kingston, Ontario)
Cihramount2
$60,000
Cihrequipment2
$0
Programname2
CIHR - ICR / Cancer Research Society Partnership - Res. Grants - Breast Cancer
Keyworddelim
Breast Cancer
; Metastasis
; Oncogenes And Tumour Suppressors
; Tumour Progression And Metastasis
Abstract
Breast cancer is the most frequently diagnosed cancer in women, killing about 680,000 people worldwide each year. Of all these women, over 90% of them die of tumor metastasis, a process in which tumors spread from the breast to other parts of the body such as lung and bone. However, treatment for metastatic breast cancer is not effective because we do not fully understand how cancer cells spread. In this research project, we will explore how a gene called PTPN12 regulates a group of genes called “Hippo” in controlling breast cancer spreading. Our studies will have great implication for the successful treatment of metastasized breast cancer in the future.
Competitiondate
202202
Approvedterm2
2 yrs 0 mth
Pinamesdelim
Yang, Xiaolong
Approvedterm
2 ans 0 mois
Cihrcontribution2
Breast Cancer Initiative~ $60,000~ $0~
