Grant: Doctoral Research Award: Canada Graduate Scholarships
University of British Columbia
$105,000.00
Spinal Cord Injury Pharmacovigilance in Canada: Using Electronic Health Data to Examine Medication Use, Adherence, and Safety
EF 2022-23
Résumé
Background and Importance: Spinal cord injury (SCI) is a debilitating neurological condition that affects many Canadians while imposing a considerable and costly burden on Canadian healthcare systems. Lifetime publicly-funded health care costs for SCI may exceed $500,000 per person. Treatment of SCI is complex and regularly involves many medications. This may increase the risk of drug-related problems, including non-adherence and unwanted drug reactions. Use of multiple medications at once in SCI may lead to complications including cognitive impairment, but more studies are needed to assess this and other risks. While medication use and safety data is important for quality SCI care, this information is lacking in Canada.
Aims & Objectives: My research objectives are to: 1) increase knowledge of medications used for SCI in Canada; 2) advance understanding of SCI medication adherence, problems, and safety; and 3) improve collaboration and knowledge sharing in SCI research.
Specific project aims include:
1. Describe trends in the use of SCI medications.
2. Examine adherence to medications used in the treatment of SCI.
3. Describe and measure unwanted effects of SCI medications, such as declines in mental health and other signs of poor health.
4. Share and discuss findings and best practices in SCI treatment with clinicians, individuals with SCI, and care partners, through in-person and virtual workshops.
This work will be done in collaboration with experts in SCI and medication use/safety, and individuals with SCI.
Expected Outcomes: My research will inform treatment guidelines and characterize the safety of SCI medications. Furthermore, study findings may identify factors associated with the use of multiple medications at once in SCI, as well as differences in medication adherence and safety by individual characteristics (like age and sex). Ultimately, this knowledge will improve SCI care and identify cost-saving opportunities for SCI treatment in Canada.
Programme
Doctoral Research Award: Canada Graduate Scholarships
Bénéficiaire
Emplacement
British Columbia, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
476041
Name
Jia Beiqi
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Musculoskeletal Health and Arthritis
Theme2
Clinical
Prcname2
Doctoral Research Awards - B
Projecttitle
Spinal Cord Injury Pharmacovigilance in Canada: Using Electronic Health Data to Examine Medication Use, Adherence, and Safety
Programtype2
Studentship Programs
Orgnameinp2
University of British Columbia
Cihramount2
$105,000
Cihrequipment2
$0
Programname2
Doctoral Research Award: Canada Graduate Scholarships
Keyworddelim
Cost-Saving Analysis; Drug Adherence; Drug Safety; Machine-Learning Algorithms; Model-Building; Pharmacoepidemiology; Pharmacological Treatment; Polypharmacy; Spinal Cord Injury; Statistical Analysis
Abstract
Background and Importance: Spinal cord injury (SCI) is a debilitating neurological condition that affects many Canadians while imposing a considerable and costly burden on Canadian healthcare systems. Lifetime publicly-funded health care costs for SCI may exceed $500,000 per person. Treatment of SCI is complex and regularly involves many medications. This may increase the risk of drug-related problems, including non-adherence and unwanted drug reactions. Use of multiple medications at once in SCI may lead to complications including cognitive impairment, but more studies are needed to assess this and other risks. While medication use and safety data is important for quality SCI care, this information is lacking in Canada.
Aims & Objectives: My research objectives are to: 1) increase knowledge of medications used for SCI in Canada; 2) advance understanding of SCI medication adherence, problems, and safety; and 3) improve collaboration and knowledge sharing in SCI research.
Specific project aims include:
1. Describe trends in the use of SCI medications.
2. Examine adherence to medications used in the treatment of SCI.
3. Describe and measure unwanted effects of SCI medications, such as declines in mental health and other signs of poor health.
4. Share and discuss findings and best practices in SCI treatment with clinicians, individuals with SCI, and care partners, through in-person and virtual workshops.
This work will be done in collaboration with experts in SCI and medication use/safety, and individuals with SCI.
Expected Outcomes: My research will inform treatment guidelines and characterize the safety of SCI medications. Furthermore, study findings may identify factors associated with the use of multiple medications at once in SCI, as well as differences in medication adherence and safety by individual characteristics (like age and sex). Ultimately, this knowledge will improve SCI care and identify cost-saving opportunities for SCI treatment in Canada.
Competitiondate
202211
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Jia, Beiqi
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $105,000~ $0~
