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Grant: CIHR New Investigator

University of Manitoba

$300,000.00

Physical Activity for Overweight Youth at Risk for Type 2 Diabetes (POWER) Trial

EF 2009-10

Résumé
In youth it remains unclear how effective physical activity is at lowering the risk for type 2 diabetes and if it does, how much activity is needed. This information is critical for developing guidelines and policies for diabetes prevention in youth. We hope to address this issue by conducting a physical activity intervention study on risk factors for type 2 diabetes in youth. We are going to test the theory that higher intensity physical activity will be better for reducing the risk for type 2 diabetes in overweight youth than lower intensity physical activity. To accomplish this aim we plan to recruit 120 overweight youth 13-18 yrs of age that have signs suggesting that they are at risk for type 2 diabetes. Eligible youth will be randomly assigned to either (1) low intensity activity; (2) high intensity activity or (3) 6-month delayed activity (control) group for a period of six months. Youth will be exercise trained at YMCA locations in Winnipeg supervised by trained staff at least 3 days each week for a period of 6 months, after which all measurements of diabetes risk will be repeated. The data will not only provide us with important information for how much physical activity an adolescent needs to reduce their risk for type 2 diabetes, but we will also gain insight into the reasons why some adolescents progress to diabetes while others remain protected. This information will help clinicians and policy makers tailor messages and practical efforts for the prevention of type 2 diabetes in the growing number of at-risk Canadian youth.
Programme
CIHR New Investigator
Emplacement
Manitoba, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
192227
Name
McGavock Jonathan M
Region
Manitoba
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Nutrition, Metabolism and Diabetes
Theme2
Clinical
Prcname2
Health Research Salary A
Projecttitle
Physical Activity for Overweight Youth at Risk for Type 2 Diabetes (POWER) Trial
Programtype2
Salary Programs
Orgnameinp2
University of Manitoba
Cihramount2
$300,000
Cihrequipment2
$0
Programname2
CIHR New Investigator
Keyworddelim
Childhood Obesity; Exercise; Lipotoxicity; Magnetic Resonance Spectroscopy; Pathogenesis; Youth-Onset Type 2 Diabetes
Abstract
In youth it remains unclear how effective physical activity is at lowering the risk for type 2 diabetes and if it does, how much activity is needed. This information is critical for developing guidelines and policies for diabetes prevention in youth. We hope to address this issue by conducting a physical activity intervention study on risk factors for type 2 diabetes in youth. We are going to test the theory that higher intensity physical activity will be better for reducing the risk for type 2 diabetes in overweight youth than lower intensity physical activity. To accomplish this aim we plan to recruit 120 overweight youth 13-18 yrs of age that have signs suggesting that they are at risk for type 2 diabetes. Eligible youth will be randomly assigned to either (1) low intensity activity; (2) high intensity activity or (3) 6-month delayed activity (control) group for a period of six months. Youth will be exercise trained at YMCA locations in Winnipeg supervised by trained staff at least 3 days each week for a period of 6 months, after which all measurements of diabetes risk will be repeated. The data will not only provide us with important information for how much physical activity an adolescent needs to reduce their risk for type 2 diabetes, but we will also gain insight into the reasons why some adolescents progress to diabetes while others remain protected. This information will help clinicians and policy makers tailor messages and practical efforts for the prevention of type 2 diabetes in the growing number of at-risk Canadian youth.
Competitiondate
200909
Approvedterm2
5 yrs 0 mth
Pinamesdelim
McGavock, Jonathan M
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $300,000~ $0~