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Grant: Discovery Grants Program - Individual

University of Ontario Institute of Technology

$35,000.00

Novel Chemical Methods for Estimating Time Since Death

EF 2011-12

Résumé
The study of decomposition chemistry is a new area of research in forensic science which investigates the chemical degradation processes that occur in the body as decomposition proceeds over time. Research in this area requires an interdisciplinary approach focusing on analytical chemistry, biological systems, soil chemistry, and environmental parameters. The aim of the research program is to investigate the unique chemical changes which occur during the decomposition of soft tissue in terrestrial environments. The biochemical degradation of the body involves the disintegration of cells and the release of degraded by-products to the surrounding environment. Analysis of lipid degradation pathways using chromatographic and spectroscopic techniques has the potential to demonstrate biochemical signatures which are modified by time and the influence of environmental parameters. These pathways have only recently been investigated and our preliminary research has demonstrated cyclic patterns of lipid degradation in soft tissue and the release of organic markers into the surrounding environment which may be correlated with the postmortem period. The major application of the research is in the rapidly growing field of forensic science. One of the most important determinants to arise in a forensic investigation is the accurate determination of time since death. Although decomposed remains are often discovered in outdoor environments, current methods for estimating this interval are unable to accurately predict the influence of environmental variables on the decomposition process, thus providing inaccurate estimations. The development of a chemical method that accounts for environmental variables will provide a novel technique and greatly enhance the accuracy of such estimations by forensic pathologists. This leading-edge research will considerably expand the minimal knowledge base relating to decomposition chemistry and will develop HQP with highly desirable skills who will promote the research excellence of Canada as sought-after members of the global forensic community.
Programme
Discovery Grants Program - Individual
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data

Tel que publié

Application id
327394-2011
Name nom
Forbes, Shari
Department département
Science, Faculty of
Organization id
19222
Institution établissement
University of Ontario Institute of Technology
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2011
Competition year année de concours
2011
Award amount
35000
Program id
RGPIN
Program nane en
Discovery Grants Program - Individual
Program name fr
Programme de subventions à la découverte - individuelles
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
1504
Committee name en
Chemistry
Committee name fr
Chimie
Area of application code
1200
Area of application group en
Advancement of knowledge
Area of application group fr
Avancement des connaissances
Area of application en
Advancement of knowledge
Area of application fr
Avancement des connaissances
Research subject code
3500
Research subject group en
Analytical chemistry
Research subject group fr
Chimie analytique
Research subject en
Analytical chemistry
Research subject fr
Chimie analytique
Partie
1
Nb partie
5
Application title
Novel Chemical Methods for Estimating Time Since Death
Keyword
NSERC
Application summary
The study of decomposition chemistry is a new area of research in forensic science which investigates the chemical degradation processes that occur in the body as decomposition proceeds over time. Research in this area requires an interdisciplinary approach focusing on analytical chemistry, biological systems, soil chemistry, and environmental parameters. The aim of the research program is to investigate the unique chemical changes which occur during the decomposition of soft tissue in terrestrial environments. The biochemical degradation of the body involves the disintegration of cells and the release of degraded by-products to the surrounding environment. Analysis of lipid degradation pathways using chromatographic and spectroscopic techniques has the potential to demonstrate biochemical signatures which are modified by time and the influence of environmental parameters. These pathways have only recently been investigated and our preliminary research has demonstrated cyclic patterns of lipid degradation in soft tissue and the release of organic markers into the surrounding environment which may be correlated with the postmortem period. The major application of the research is in the rapidly growing field of forensic science. One of the most important determinants to arise in a forensic investigation is the accurate determination of time since death. Although decomposed remains are often discovered in outdoor environments, current methods for estimating this interval are unable to accurately predict the influence of environmental variables on the decomposition process, thus providing inaccurate estimations. The development of a chemical method that accounts for environmental variables will provide a novel technique and greatly enhance the accuracy of such estimations by forensic pathologists. This leading-edge research will considerably expand the minimal knowledge base relating to decomposition chemistry and will develop HQP with highly desirable skills who will promote the research excellence of Canada as sought-after members of the global forensic community.