Grant: Collaborative Health Research Projects (NSERC partnered)
University of Alberta
$315,794.00
Development of an ex vivo heart perfusion system for pre-transplant preservation and evaluation of donor hearts
EF 2016-17
Résumé
Cardiac transplantation remains the gold standard therapy for the definitive treatment of end-stage heart failure. However the wider application of this life saving intervention is limited by the short supply of donor organs. Compounding this problem is a high frequency of poor heart function observed in the multi-organ donor, resulting in a low utilization rate of hearts that are offered. We are developing a device that will provide continuous warm blood-based perfusion of the donor heart, permitting optimal preservation of the organ as well as functional assessment.
Programme
Collaborative Health Research Projects (NSERC partnered)
Bénéficiaire
Emplacement
Alberta, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
361038
Name
Freed Darren H
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Partnername
Natural Sciences and Engineering Research Council of Canada (NSERC)
Instname2
Circulatory and Respiratory Health
Theme2
Biomedical
Prcname2
Collaborative Health Research Projects - NSERC Partnered
Projecttitle
Development of an ex vivo heart perfusion system for pre-transplant preservation and evaluation of donor hearts
Programtype2
Operating Grants
Orgnameinp2
University of Alberta
Cihramount2
$315,794
Cihrequipment2
$0
Programname2
Collaborative Health Research Projects (NSERC partnered)
Keyworddelim
Heart Transplantation; Organ Perfusion And Preservation
Abstract
Cardiac transplantation remains the gold standard therapy for the definitive treatment of end-stage heart failure. However the wider application of this life saving intervention is limited by the short supply of donor organs. Compounding this problem is a high frequency of poor heart function observed in the multi-organ donor, resulting in a low utilization rate of hearts that are offered. We are developing a device that will provide continuous warm blood-based perfusion of the donor heart, permitting optimal preservation of the organ as well as functional assessment.
Competitiondate
201610
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Freed, Darren H; Nobes, David S
Approvedterm
3 ans 0 mois
Cihrcontribution2
Major Initiatives #2~ $315,794~ $0~
