Grant: Research Tools and Instruments - Category 1 (<$150,000)
Queen's University
$150,000.00
HPLC-DAD-MS system
EF 2011-12
Résumé
The HPLC-DAD-MS system is an analytical instrument that can isolate molecules from a complex mixture and subsequently identify unique spectroscopic features for each molecule. Such data is tremendously useful for the analysis of the products of chemical reactions and the contents of bioactive extracts derived from natural sources. This fully automated instrument can also process dozens of samples each day. For these reasons HPLC-DAD-MS systems are widely used in pharmaceutical and biotechnology companies. To better prepare our graduate students for the workplace, the HPLC-DAD-MS system described in this proposal will be used by 56 students from five research groups to obtain extensive hands-on training and experience, as well as accelerate their research in a number of programs. This includes the biosynthesis of drug-like molecules by soil bacteria, enzyme catalysis, repair of damaged DNA with artificial receptors, extraction of oils using green solvent systems, the development of miniature analytical devices, and the development of a novel reaction for the synthesis of complex molecules.
Programme
Research Tools and Instruments - Category 1 (<$150,000)
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data
Tel que publié
Application id
422374-2012
Name nom
Zechel, David
Department département
Chemistry
Organization id
29
Institution établissement
Queen's University
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2011
Competition year année de concours
2012
Award amount
150000
Program id
EQPEQ
Program nane en
Research Tools and Instruments - Category 1 (<$150,000)
Program name fr
Outils et instruments de recherche - catégorie 1 (<150 000$)
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
1501
Committee name en
Genes, Cells and Molecules
Committee name fr
Gènes, cellules et molécules
Area of application code
1103
Area of application group en
Health, education and social services
Area of application group fr
Santé publique, éducation et services sociaux
Area of application en
Learning and education
Area of application fr
Apprentissage et éducation
Research subject code
3503
Research subject group en
Analytical chemistry
Research subject group fr
Chimie analytique
Research subject en
Separation methods
Research subject fr
Méthodes de séparation
Partie
1
Nb partie
1
Application title
HPLC-DAD-MS system
Keyword
NSERC
Application summary
The HPLC-DAD-MS system is an analytical instrument that can isolate molecules from a complex mixture and subsequently identify unique spectroscopic features for each molecule. Such data is tremendously useful for the analysis of the products of chemical reactions and the contents of bioactive extracts derived from natural sources. This fully automated instrument can also process dozens of samples each day. For these reasons HPLC-DAD-MS systems are widely used in pharmaceutical and biotechnology companies. To better prepare our graduate students for the workplace, the HPLC-DAD-MS system described in this proposal will be used by 56 students from five research groups to obtain extensive hands-on training and experience, as well as accelerate their research in a number of programs. This includes the biosynthesis of drug-like molecules by soil bacteria, enzyme catalysis, repair of damaged DNA with artificial receptors, extraction of oils using green solvent systems, the development of miniature analytical devices, and the development of a novel reaction for the synthesis of complex molecules.
