Grant: Research Tools and Instruments - Category 1 (<$150,000)
École de technologie supérieure
$92,452.00
Rheometer for the optimization and characterization of embolizing gels
EF 2009-10
Résumé
The rheometer requested will be shared by two researchers located at the CHUM research center (CRCHUM). This equipment with allow to characterize hydrogels and other soft synthetic and biological tissues, for several innovations in the biomedical field. The research program aims to optimize promising embolizing agents for minimally invasive treatments of vascular diseases. Lerouge's Canada Research Chair on Endovascular Implants and Biomaterials is currently developing new approaches and materials to provide safe and efficient treatments. The rheometer will be used to characterize and optimize radioopaque thermogels, which are liquid at room temperature and gelling at body temperature. The equipment will also be utilized to validate a new innovative rheometry technique and to characterize materials used for the validation of elastography techniques developed by Cloutier, director of the Laboratory of Biorheology and Medical Ultrasonics (LBUM) at the CRCHUM. These new elastrography imaging methods possess a great potential in view of the fact that they can determine the mechanical properties of observed biological tissues. In both cases, extensive characterization of soft materials involved (hydrogel, biological tissues or tissue-mimicking materials) is required. The rheometer requested will allow testing of viscous solutions, gels and pastes, at controlled temperatures. The system chosen is well adapted for high precision research as well as student training, since it includes an easy set up to minimize operator errors. Preliminary promising data were obtained with an old rheometer which is used to study bitumen at École de technologie supérieure (ÉTS). But its lack of availability, the distance between the CRCHUM and ÉTS and more particularly the impossibility to use this system with biological products make the purchase of a new dedicated rheometer absolutely necessary to achieve the proposed research program and bring these innovations into the clinical reality.
Programme
Research Tools and Instruments - Category 1 (<$150,000)
Bénéficiaire
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data
Tel que publié
Application id
390101-2010
Name nom
Lerouge, Sophie
Department département
Génie mécanique
Organization id
53
Institution établissement
École de technologie supérieure
Province en
Québec
Province fr
Québec
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2009
Competition year année de concours
2010
Award amount
92452
Program id
EQPEQ
Program nane en
Research Tools and Instruments - Category 1 (<$150,000)
Program name fr
Outils et instruments de recherche - catégorie 1 (<150 000$)
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
1511
Committee name en
Materials and Chemical Engineering
Committee name fr
Génie chimique et des matériaux
Area of application code
1102
Area of application group en
Health, education and social services
Area of application group fr
Santé publique, éducation et services sociaux
Area of application en
Biomedical engineering
Area of application fr
Génie biomédical
Research subject code
1902
Research subject group en
Biomedical engineering
Research subject group fr
Génie biomédical
Research subject en
Biomedical materials
Research subject fr
Matériaux biomédicaux
Partie
1
Nb partie
1
Application title
Rheometer for the optimization and characterization of embolizing gels
Keyword
NA
Application summary
The rheometer requested will be shared by two researchers located at the CHUM research center (CRCHUM). This equipment with allow to characterize hydrogels and other soft synthetic and biological tissues, for several innovations in the biomedical field. The research program aims to optimize promising embolizing agents for minimally invasive treatments of vascular diseases. Lerouge's Canada Research Chair on Endovascular Implants and Biomaterials is currently developing new approaches and materials to provide safe and efficient treatments. The rheometer will be used to characterize and optimize radioopaque thermogels, which are liquid at room temperature and gelling at body temperature. The equipment will also be utilized to validate a new innovative rheometry technique and to characterize materials used for the validation of elastography techniques developed by Cloutier, director of the Laboratory of Biorheology and Medical Ultrasonics (LBUM) at the CRCHUM. These new elastrography imaging methods possess a great potential in view of the fact that they can determine the mechanical properties of observed biological tissues. In both cases, extensive characterization of soft materials involved (hydrogel, biological tissues or tissue-mimicking materials) is required. The rheometer requested will allow testing of viscous solutions, gels and pastes, at controlled temperatures. The system chosen is well adapted for high precision research as well as student training, since it includes an easy set up to minimize operator errors. Preliminary promising data were obtained with an old rheometer which is used to study bitumen at École de technologie supérieure (ÉTS). But its lack of availability, the distance between the CRCHUM and ÉTS and more particularly the impossibility to use this system with biological products make the purchase of a new dedicated rheometer absolutely necessary to achieve the proposed research program and bring these innovations into the clinical reality.
