Grant: Operating Grant
Université Laval
$918,695.00
Role of iNOS in the pathogenesis of insulin resistance
EF 2010-11
Résumé
The principal goal of this project in to understand how iNOS, a pro-inflammatory mediator, promotes insulin resistance which can lead to diabetes in obese individuals. We hope that the proposed research will unravel the molecular and cellular mechanisms behind iNOS-driven insulin resistance and thus help develop novel treatments for obese diabetic individuals.
Programme
Operating Grant
Bénéficiaire
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
210554
Name
Marette André
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Nutrition, Metabolism and Diabetes
Theme2
Biomedical
Prcname2
Diabetes, Obesity, Lipid & Lipoprotein Disorders
Projecttitle
Role of iNOS in the pathogenesis of insulin resistance
Programtype2
Operating Grants
Orgnameinp2
Université Laval
Cihramount2
$918,695
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Adiponectin; Adipose Tissue; Ampk; Enos; Glucose Metabolism; Inos
Abstract
The principal goal of this project in to understand how iNOS, a pro-inflammatory mediator, promotes insulin resistance which can lead to diabetes in obese individuals. We hope that the proposed research will unravel the molecular and cellular mechanisms behind iNOS-driven insulin resistance and thus help develop novel treatments for obese diabetic individuals.
Competitiondate
201009
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Marette, André
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $918,695~ $0~
