Grant: Operating Grant
McGill University
$625,814.00
Coordination of Spindle Assembly and Function by the g-Tubulin Complex
EF 2011-12
Résumé
In order to divide, cells must coordinate the completion of DNA replication with growth and assembly of the mitotic spindle,which will segregate the chromosomes into daughter cells. The research program will investigate how cells use a biochemical version of a traffic "hub" to process information that must be transferred from one location in the cell to another in order to achieve this coordination. These control principles ensure proper "decision-making" during the assembly of the mitotic spindle, an essential part of the biological machinery that ensures daughter cells receive a complete set of chromosomes at the end of each cell division.
Programme
Operating Grant
Bénéficiaire
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
255254
Name
Vogel Jackie
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Genetics
Theme2
Biomedical
Prcname2
Cell Physiology
Projecttitle
Coordination of Spindle Assembly and Function by the g-Tubulin Complex
Programtype2
Operating Grants
Orgnameinp2
McGill University
Cihramount2
$625,814
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Automated Tracking And Feature Finding; Cell Biology And Molecular Genetics; Cell Divison; Computational Biology; Cytoskeleton; Experimental Biophysics; Genomics; Intracellular Signaling; Microscopy And Image Analysis; Proteomics
Abstract
In order to divide, cells must coordinate the completion of DNA replication with growth and assembly of the mitotic spindle,which will segregate the chromosomes into daughter cells. The research program will investigate how cells use a biochemical version of a traffic "hub" to process information that must be transferred from one location in the cell to another in order to achieve this coordination. These control principles ensure proper "decision-making" during the assembly of the mitotic spindle, an essential part of the biological machinery that ensures daughter cells receive a complete set of chromosomes at the end of each cell division.
Competitiondate
201203
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Vogel, Jackie
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $625,814~ $0~
