Grant: Operating Grant

The mammalian olfactory system retains remarkable capacity to detect and discriminate odors despite continuous turnover of olfactory bulb neurons. New cells are constantly integrating into the pre-existing neuronal network in the olfactory bulb. The exact role of new neurons in the adult olfactory bulb and odor behavior remains elusive despite continues progress. In the last years we discovered that newborn cells can de subdivided to distinct subtypes that may play different role in the olfactory bulb network functioning and odor behavior. The research program undertaken under this proposal is aimed at investigating the role of distinct subtypes of new neurons in the adult olfactory bulb network functioning and odor behaviour.