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Grant: Project Grant

University of British Columbia

$944,776.00

A prospective and longitudinal investigation of concussive and subconcussive mild traumatic brain injury mechanisms in ice hockey

EF 2019-20

Résumé
Sports concussion is a major public health concern. Even more alarmingly, recent findings show that repeated subconcussive head impacts in sports may also lead to long-term brain changes. Despite the prevalence of sports-related brain injuries, we still have very limited understanding of how the forces in head impacts result in brain trauma, and even less is known about how trauma accumulates through multiple impacts. In this study, we will instrument ice hockey athletes with wearable sensors to measure impact forces and accelerations, paired with assessments of their brain structure / function using imaging, neurocognitive, and blood testing at multiple time points across three seasons. Novel imaging techniques and blood biomarkers can identify subtle structural changes in the brain that are often missed in conventional brain imaging, and a sensitive neurocognitive test battery can help detect changes in brain function. With these data, we will investigate the mechanisms of acute and long-term trauma from concussions and subconcussive head impacts. Our findings may lead to novel diagnostic technologies for sports brain injury, inform return-to-play decisions, as well as identify the effects of repeated head impact exposure on brain structure and function. This will guide concussion management in sports, and inform rule changes to limit head impact exposure to a safe level.
Programme
Project Grant
Emplacement
British Columbia, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
419138
Name
Wu Lyndia (Chun)
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Neurosciences, Mental Health and Addiction
Theme2
Biomedical
Prcname2
Behavioural Sciences - B-2
Projecttitle
A prospective and longitudinal investigation of concussive and subconcussive mild traumatic brain injury mechanisms in ice hockey
Programtype2
Operating Grants
Orgnameinp2
University of British Columbia
Cihramount2
$944,776
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Concussion Neuroimaging; Concussion Recovery; Head Impact Sensing; Injury Biomechanics; Injury Mechanism; Mild Traumatic Brain Injury; Myelin Imaging; Neurocognitive Assessments; Prospective Longitudinal Study; Subconcussive Head Impacts
Abstract
Sports concussion is a major public health concern. Even more alarmingly, recent findings show that repeated subconcussive head impacts in sports may also lead to long-term brain changes. Despite the prevalence of sports-related brain injuries, we still have very limited understanding of how the forces in head impacts result in brain trauma, and even less is known about how trauma accumulates through multiple impacts. In this study, we will instrument ice hockey athletes with wearable sensors to measure impact forces and accelerations, paired with assessments of their brain structure / function using imaging, neurocognitive, and blood testing at multiple time points across three seasons. Novel imaging techniques and blood biomarkers can identify subtle structural changes in the brain that are often missed in conventional brain imaging, and a sensitive neurocognitive test battery can help detect changes in brain function. With these data, we will investigate the mechanisms of acute and long-term trauma from concussions and subconcussive head impacts. Our findings may lead to novel diagnostic technologies for sports brain injury, inform return-to-play decisions, as well as identify the effects of repeated head impact exposure on brain structure and function. This will guide concussion management in sports, and inform rule changes to limit head impact exposure to a safe level.
Competitiondate
202003
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Wu, Lyndia (Chun); Rauscher, Alexander; van Donkelaar, Paul
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $944,776~ $0~