Grant: Canada Research Chairs
University of Calgary
$200,000.00
Environmental Physiology and Toxicology
EF 2024-25
Résumé
My research aims to uncover the molecular mechanisms that allow animals to cope with stress. Specifically, my research will focus on glucocorticoid signalling, a conserved stress coping pathway, which is essential for all aspects of animal growth and welfare. We have genetically edited zebrafish to elucidate the mechanisms involved in stress coping by deleting stress-related genes. These knockout models will allow us to identify emerging contaminants targeting the stress axis and reducing animal fitness. My lab will also determine the mechanisms leading to long-term and multigenerational impacts on stress and growth performances in response to developmental exposure to environmental contaminants.
Programme
Canada Research Chairs
Bénéficiaire
Emplacement
Alberta, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data
Tel que publié
Application id
CRC-2018-00233
Name nom
Vijayan, Mathilakath
Department département
Biological Sciences - University of Calgary
Organization id
11
Institution établissement
University of Calgary
Province en
Alberta
Province fr
Alberta
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2024
Competition year année de concours
2018
Award amount
200000
Program id
CRC
Program name en
Canada Research Chairs
Program name fr
Chaires de recherche du Canada
Group en
DISCOVERY RESEARCH
Group fr
RECHERCHE AXÉE SUR LA DÉCOUVERTE
Committee code
9998
Committee name en
Canada Research Chair Selection Committee
Committee name fr
Comité de sélection des Chaires de recherche du Canada
Area of application code
9999
Area of application group en
Not available
Area of application group fr
Non disponible
Area of application en
Not available
Area of application fr
Non disponible
Research subject code
9999
Research subject group en
Not available
Research subject group fr
Non disponible
Research subject en
Not available
Research subject fr
Non disponible
Field of research list codes
RDF3020206
Field of research list names en
Human endocrinology (except diabetes and obesity)
Field of research list names fr
Endocrinologie humaine (sauf le diabète et l'obésité)
Socioeconomic objective list names en
Not available
Socioeconomic objective list names fr
Non disponible
Application title
Environmental Physiology and Toxicology
Keywords
Fish; Stress Physiology; Ecotoxicology; Environmental genomics; Endocrine disruption; Corticosteroids; Stress signalling
Application summary
My research aims to uncover the molecular mechanisms that allow animals to cope with stress. Specifically, my research will focus on glucocorticoid signalling, a conserved stress coping pathway, which is essential for all aspects of animal growth and welfare. We have genetically edited zebrafish to elucidate the mechanisms involved in stress coping by deleting stress-related genes. These knockout models will allow us to identify emerging contaminants targeting the stress axis and reducing animal fitness. My lab will also determine the mechanisms leading to long-term and multigenerational impacts on stress and growth performances in response to developmental exposure to environmental contaminants.
