Grant: Operating Grant

Tremendous biotechnological advances in the last 15-20 years have enabled measurements of massive amounts of biological signals in our genes and their functions in a single test. These emerging laboratory technologies are changing the ways biologists and clinicians study human health and diseases. These will lead to new methods of detecting disease early to save both lives and medical costs substantially, and treating patients effectively in a tailored way without side effects. There is a new research challenge, however, that needs to be overcome for these technologies to fulfill these promises. Specifically, we must first discover the biologically and clinically meaningful patterns in these massive amounts of data. This project addresses such statistical and bioinformatics challenges in discovery of patterns in massive biological databases in modern health sciences.