Grant: Canadian Microbiome Initiative - LOI
McMaster University
$0.00
The role of the intestinal microbiota in highly prevalent and sometimes co-morbid conditions associated with low grade inflammation: functional GI disorders, obesity and depression.
EF 2009-10
Résumé
The gut is inhabited my millions of bacteria that normally reside in harmony with us and contribute to our health. They impact on many of our functions that include not only digestion, but also our body weight and behavior. There is emerging evidence that changes occur in the bacterial community of individuals with certain digestive disorders and in obesity. There is experimental evidence that these bacteria can influence behavior. We will study gut bacterial profiles in individuals with digestive disorders like Irritable Bowel Syndrome, in obese subjects before and after by-pass surgery and in newly diagnosed patients with depression. We will then analyze the genetic and chemical composition of bacteria to determine how they contribute to these diseases, and thus evelop new therapies
Programme
Canadian Microbiome Initiative - LOI
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
196856
Name
Collins Stephen M
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Infection and Immunity
Theme2
Biomedical
Prcname2
Emerging Team Grant: Canadian Microbiome Initiative
Projecttitle
The role of the intestinal microbiota in highly prevalent and sometimes co-morbid conditions associated with low grade inflammation: functional GI disorders, obesity and depression.
Programtype2
Operating Grants
Orgnameinp2
McMaster University
Cihramount2
$0
Cihrequipment2
$0
Programname2
Canadian Microbiome Initiative - LOI
Keyworddelim
Biochemistry; Bioinformatics; Depression; Gastrointestinal Disease; Microbiology; Obesity
Abstract
The gut is inhabited my millions of bacteria that normally reside in harmony with us and contribute to our health. They impact on many of our functions that include not only digestion, but also our body weight and behavior. There is emerging evidence that changes occur in the bacterial community of individuals with certain digestive disorders and in obesity. There is experimental evidence that these bacteria can influence behavior. We will study gut bacterial profiles in individuals with digestive disorders like Irritable Bowel Syndrome, in obese subjects before and after by-pass surgery and in newly diagnosed patients with depression. We will then analyze the genetic and chemical composition of bacteria to determine how they contribute to these diseases, and thus evelop new therapies
Competitiondate
200911
Approvedterm2
0 yr 0 mth
Pinamesdelim
Collins, Stephen M; Brown, Eric D; Neufeld, Josh D
Approvedterm
0 an 0 mois
