Grant: Project Grant
University of Ottawa
$416,924.00
Inhibiting Ice Recrystallization - A Strategy to Enable Cellular Therapies.
EF 2016-17
Résumé
Cell-based therapeutics have emerged as a critical aspect of modern health care and have shaped new models of care in stem cell therapy, regenerative medicine and transfusion practices. Unfortunately, current cryopreservation protocols remain suboptimal and limit the effectiveness of hematopoietic stem cells (HSC) from human umbilical cord blood and red blood cells (RBCs). Improved cryopreservation methods that specifically inhibit ice
recrystallization will increase the success of such therapies, dramatically improve outcomes for patients and ultimately improve storage and distribution of these cellular products.
Programme
Project Grant
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
356621
Name
Ben Robert N
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Circulatory and Respiratory Health
Theme2
Biomedical
Prcname2
Project Grant Competition
Projecttitle
Inhibiting Ice Recrystallization - A Strategy to Enable Cellular Therapies.
Programtype2
Operating Grants
Orgnameinp2
University of Ottawa
Cihramount2
$416,924
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Carbohydrate Chemistry; Cryopreservation; Engraftment; Hematopoietic Stem Cells; Ice Recrystallization; Inhibitors; Organic Synthesis; Red Blood Cells; Regenerative Medicine; Umbilical Cord Blood
Abstract
Cell-based therapeutics have emerged as a critical aspect of modern health care and have shaped new models of care in stem cell therapy, regenerative medicine and transfusion practices. Unfortunately, current cryopreservation protocols remain suboptimal and limit the effectiveness of hematopoietic stem cells (HSC) from human umbilical cord blood and red blood cells (RBCs). Improved cryopreservation methods that specifically inhibit ice
recrystallization will increase the success of such therapies, dramatically improve outcomes for patients and ultimately improve storage and distribution of these cellular products.
Competitiondate
201610
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Ben, Robert N
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $416,924~ $0~
