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Grant: Project Grant

Research Institute of the McGill University Health Centre

$374,851.00

Feasibility of an innovative AideSmart! app-based multiplexed, point-of-care screening/counselling strategy for HIV-associated co-infections (HCV, Syphilis, HBV) in key Canadian populations

EF 2016-17

Résumé
An estimated 40-50% of Canadians infected are unaware of their hepatitis C infection, 18-28% of their HIV, and 15-20% of their hepatitis B or syphilis infection. Gaps in timely access to care, population engagement, stigma and discrimination, limited clinic hours, limited testing in remote communities and long turnaround time for results lead to individuals not getting tested, or not coming back for their results, precipitate losses to follow up with conventional testing. Despite treatment availability, undiagnosed individuals fuel the ongoing transmission of these infections, and knowing one's co-infection status is the first step towards infection control. New simple rapid tests that can diagnose multiple infections with one device, together with mobile applications that can integrate counselling, quality testing, linkages to care, communications and data storage, make up a powerful strategy to potentially address the problem. We have recently successfully pilot tested this strategy in India with pregnant women in a remote setting. In this project, we will adapt and test our Smart App/Multiplex rapid testing, screening and counselling strategy in key populations residing in Ontario, Quebec, Alberta and Nova Scotia. For this, over a 3-year period, we will recruit 450 participants who will use the new strategy, and we will test how many participants complete the process (including testing, counselling and care), ask them about preference and acceptability. Data from this study will guide us for a clinical trial Canadawide.
Programme
Project Grant
Emplacement
Quebec, Canada
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
357577
Name
Pai Nitika
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Health Services and Policy Research
Theme2
Health systems / services
Prcname2
Project Grant Competition
Projecttitle
Feasibility of an innovative AideSmart! app-based multiplexed, point-of-care screening/counselling strategy for HIV-associated co-infections (HCV, Syphilis, HBV) in key Canadian populations
Programtype2
Operating Grants
Orgnameinp2
Research Institute of the McGill University Health Centre
Cihramount2
$374,851
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Co-Infections; Hepatitis B,; Hepatitis C; Hiv/Aids; Innovative Smart Applications; Mhealth; Multiplex; Point-Of-Care Tests; Sexually Transmitted And Blood Borne Infections; Syphilis
Abstract
An estimated 40-50% of Canadians infected are unaware of their hepatitis C infection, 18-28% of their HIV, and 15-20% of their hepatitis B or syphilis infection. Gaps in timely access to care, population engagement, stigma and discrimination, limited clinic hours, limited testing in remote communities and long turnaround time for results lead to individuals not getting tested, or not coming back for their results, precipitate losses to follow up with conventional testing. Despite treatment availability, undiagnosed individuals fuel the ongoing transmission of these infections, and knowing one's co-infection status is the first step towards infection control. New simple rapid tests that can diagnose multiple infections with one device, together with mobile applications that can integrate counselling, quality testing, linkages to care, communications and data storage, make up a powerful strategy to potentially address the problem. We have recently successfully pilot tested this strategy in India with pregnant women in a remote setting. In this project, we will adapt and test our Smart App/Multiplex rapid testing, screening and counselling strategy in key populations residing in Ontario, Quebec, Alberta and Nova Scotia. For this, over a 3-year period, we will recruit 450 participants who will use the new strategy, and we will test how many participants complete the process (including testing, counselling and care), ask them about preference and acceptability. Data from this study will guide us for a clinical trial Canadawide.
Competitiondate
201610
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Pai, Nitika; Engel, Nora; Kaufman, Jay S; Kim, John E; Wong, Thomas
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $374,851~ $0~