Grant: Operating Grant

Inflammation is a term that describes how our body's immune system reacts to damaged tissues, infections or the presence of agents that cause irritations such as allergens. If the tissue or organ involved is progressively damaged or if an infection or irritant persist, the resulting inflammatory responses become chronic leading to a range of immune response-related diseases, exemplified by medical conditions such as hay fever, atherosclerosis, Crohn's disease and rheumatoid arthritis. In this proposal, we plan to generate synthetic, targeted biomolecules that will specifically block or dampen uncontrolled immune responses.