Grant: Project Grant
University of Alberta
$707,625.00
Molecular imaging of autotaxin: Targeting the crossroad of cancer and inflammation
EF 2018-19
Résumé
The proposed health research project aims at the development of a medical imaging assay using a novel class of drugs exerting combined anti-inflammatory and anti-cancer effects. The novel drug molecules are decorated with a radioactive atom to detect chronic inflammatory diseases like fibrosis and cancer in patients at an early disease stage with high accuracy. The novel medical imaging assay will allow physicians to look into the patient's body from the outside to find inflamed and cancerous tissue. The technology will enable physicians to select patients for the most optimal treatment option using innovative hybrid anti-inflammatory and anti-cancer drugs. This concept is in alignment with the prominent principle "to select the right treatment-for the right patient-at the right time". The treatment success and response can also be monitored with the novel medical imaging assay. A task of this magnitude is only achievable with a strong team of cancer research experts and strong partners from the health service and industrial community. Such a team has been assembled for the project to ultimately enhance patient care, especially with difficult to treat diseases like chronic inflammation and cancer.
Programme
Project Grant
Bénéficiaire
Emplacement
Alberta, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
388574
Name
Wuest Frank
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Pharmaceutical Sciences
Projecttitle
Molecular imaging of autotaxin: Targeting the crossroad of cancer and inflammation
Programtype2
Operating Grants
Orgnameinp2
University of Alberta
Cihramount2
$707,625
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Autotaxin; Cancer; Fibrosis; Inflammation; Molecular Imaging; Positron Emission Tomography
Abstract
The proposed health research project aims at the development of a medical imaging assay using a novel class of drugs exerting combined anti-inflammatory and anti-cancer effects. The novel drug molecules are decorated with a radioactive atom to detect chronic inflammatory diseases like fibrosis and cancer in patients at an early disease stage with high accuracy. The novel medical imaging assay will allow physicians to look into the patient's body from the outside to find inflamed and cancerous tissue. The technology will enable physicians to select patients for the most optimal treatment option using innovative hybrid anti-inflammatory and anti-cancer drugs. This concept is in alignment with the prominent principle "to select the right treatment-for the right patient-at the right time". The treatment success and response can also be monitored with the novel medical imaging assay. A task of this magnitude is only achievable with a strong team of cancer research experts and strong partners from the health service and industrial community. Such a team has been assembled for the project to ultimately enhance patient care, especially with difficult to treat diseases like chronic inflammation and cancer.
Competitiondate
201809
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Wuest, Frank
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $707,625~ $0~