Grant: CIHR-ICRH Travel Awards - General pool
University of Alberta
$1,500.00
Membrane-Impermeable Glucocorticoids Act on Membrane-Associated Receptors in the Nucleus of the Solitary Tract to Affect Hepatic VLDL-TG Secretion
EF 2023-24
Résumé
Glucocorticoids (GCs) are known to regulate peripheral lipid metabolism through action on peripheral organs. However, the brain is becoming more well known for its ability to also partake in regulating lipid metabolism. GCs have been shown to act in the Nucleus of the Solitary Tract (NTS) to increase triglyceride secretion from the liver. These effects were observed in a timeframe that cannot be explained through classical genomic mechanisms. We here investigate if GCs can act via a membrane-associated receptor in the NTS affect liver lipid metabolism.
Programme
CIHR-ICRH Travel Awards - General pool
Bénéficiaire
Emplacement
Alberta, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
495586
Name
Vasilev Boyan
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Prcname2
Special Cases
Projecttitle
Membrane-Impermeable Glucocorticoids Act on Membrane-Associated Receptors in the Nucleus of the Solitary Tract to Affect Hepatic VLDL-TG Secretion
Programtype2
Undefined
Orgnameinp2
University of Alberta
Cihramount2
$1,500
Cihrequipment2
$0
Programname2
CIHR-ICRH Travel Awards - General pool
Keyworddelim
Glucocorticoids
Abstract
Glucocorticoids (GCs) are known to regulate peripheral lipid metabolism through action on peripheral organs. However, the brain is becoming more well known for its ability to also partake in regulating lipid metabolism. GCs have been shown to act in the Nucleus of the Solitary Tract (NTS) to increase triglyceride secretion from the liver. These effects were observed in a timeframe that cannot be explained through classical genomic mechanisms. We here investigate if GCs can act via a membrane-associated receptor in the NTS affect liver lipid metabolism.
Competitiondate
202309
Approvedterm2
1 yr 0 mth
Pinamesdelim
Vasilev, Boyan
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $1,500~ $0~
