Grant: Operating Grant

Chronic kidney disease affects a large proportion of the population. Patients with chronic kidney disease experience a number of problems, including a risk of developing kidney failure that would require dialysis or a kidney transplant. Unfortunately, since the understanding is poor, there are almost no specific therapies for chronic kidney disease or to prevent the development of kidney failure. This proposal will examine how genes that control inflammation can affect kidney disease and the development of kidney failure. This research will increase the understanding of kidney disease that will lead to the development of new treatments or diagnostic tests.