Grant: Research Tools and Instruments - Category 1 (<$150,000)
University of Western Ontario
$140,254.00
An ultrasound imaging system for tissue elastography
EF 2008-09
Résumé
BACKGROUND: Early detection of cancer is one of the primary requirements of its successful treatment. Elastography, which images tissue stiffness, has recently emerged as a promising diagnostic tool for this purpose. In ultrasound elastography the tissue is compressed and tissue deformation is measured using conventional ultrasound machines to construct elastography images. To exploit the potentials of ultrasound elastography, it is necessary to acquire an imaging system with open access to its raw deformation data.
OBJECTIVES: We shall develop novel ultrasound elastography systems for early and accurate diagnosis and treatment of breast, prostate and lung cancers. More specifically we shall develop elastography systems for cancer detection and biopsy guidance of breast and prostate, and a guidance system for lung brachytherapy.
SCIENTIFIC APPROACH: Using the proposed ultrasound system, we shall gain access to the tissue deformation data and use it to develop high quality ultrasound elastography systems for imaging the breast and prostate and lung. The data open access feature of the proposed system will allow its integration with a force measurement system currently under development in our lab to enhance its quality for breast cancer detection and biopsy. We shall rigorously evaluate our algorithms and systems using tissue-mimicking phantoms.
NOVEL ASPECTS: The proposed ultasound equipment has a unique feature of open access to its raw data. This feature will lead to rapid development of high quality ultrasound elastography images. Furthermore, the novel concepts used in our developing elastography systems will benefit greatly from the proposed equipments, as the required tissue deformation data are readily available for incorporation into the systems.
SIGNIFICANCE: The proposed ultrasound equipments will be used for developing several ultrasound elastography systems. Two systems will be developed for more accurate and early cancer detection and biopsy guidance of the breast and prostate. Another system will be developed for lung brachytherpay. These systems can potentially reduce the possibility of misdiagnosis and cancer recurrence, thus reducing health care cost.
Programme
Research Tools and Instruments - Category 1 (<$150,000)
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data
Tel que publié
Application id
376231-2009
Name nom
Samani, Abbas
Department département
Electrical and Computer Engineering
Organization id
36
Institution établissement
University of Western Ontario
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2008
Competition year année de concours
2009
Award amount
140254
Program id
EQPEQ
Program nane en
Research Tools and Instruments - Category 1 (<$150,000)
Program name fr
Outils et instruments de recherche - catégorie 1 (<150 000$)
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
1053
Committee name en
Mechanical Engineering - A
Committee name fr
Génie mécanique - A
Area of application code
1102
Area of application group en
Health, education and social services
Area of application group fr
Santé publique, éducation et services sociaux
Area of application en
Biomedical engineering
Area of application fr
Génie biomédical
Research subject code
1900
Research subject group en
Biomedical engineering
Research subject group fr
Génie biomédical
Research subject en
Biomedical engineering
Research subject fr
Génie biomédical
Partie
1
Nb partie
1
Application title
An ultrasound imaging system for tissue elastography
Keyword
NA
Application summary
BACKGROUND: Early detection of cancer is one of the primary requirements of its successful treatment. Elastography, which images tissue stiffness, has recently emerged as a promising diagnostic tool for this purpose. In ultrasound elastography the tissue is compressed and tissue deformation is measured using conventional ultrasound machines to construct elastography images. To exploit the potentials of ultrasound elastography, it is necessary to acquire an imaging system with open access to its raw deformation data.
OBJECTIVES: We shall develop novel ultrasound elastography systems for early and accurate diagnosis and treatment of breast, prostate and lung cancers. More specifically we shall develop elastography systems for cancer detection and biopsy guidance of breast and prostate, and a guidance system for lung brachytherapy.
SCIENTIFIC APPROACH: Using the proposed ultrasound system, we shall gain access to the tissue deformation data and use it to develop high quality ultrasound elastography systems for imaging the breast and prostate and lung. The data open access feature of the proposed system will allow its integration with a force measurement system currently under development in our lab to enhance its quality for breast cancer detection and biopsy. We shall rigorously evaluate our algorithms and systems using tissue-mimicking phantoms.
NOVEL ASPECTS: The proposed ultasound equipment has a unique feature of open access to its raw data. This feature will lead to rapid development of high quality ultrasound elastography images. Furthermore, the novel concepts used in our developing elastography systems will benefit greatly from the proposed equipments, as the required tissue deformation data are readily available for incorporation into the systems.
SIGNIFICANCE: The proposed ultrasound equipments will be used for developing several ultrasound elastography systems. Two systems will be developed for more accurate and early cancer detection and biopsy guidance of the breast and prostate. Another system will be developed for lung brachytherpay. These systems can potentially reduce the possibility of misdiagnosis and cancer recurrence, thus reducing health care cost.
