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Grant: Doctoral Research Award: Canada Graduate Scholarships

Queen's University (Kingston, Ontario)

$120,000.00

The Role of Neuroinflammation in Clinical Presentations of Fibromyalgia

EF 2024-25

Résumé
Fibromyalgia is a medical condition characterized by chronic widespread pain, fatigue, sleep disturbance, cognitive impairment, and psychological disorders. These symptoms negatively affect patients' physical, psychological, and social well-being, including loss of employment, poor mental health, and social isolation, resulting in greatly reduced quality of life. Currently, there is no ideal treatment for fibromyalgia due to our limited understanding of its causes, and the differences in the symptoms and severity of symptoms that patients experience. Research suggests inflammation in the nervous system or, neuroinflammation, can contribute to the development and maintenance of chronic pain conditions. Importantly, neuroinflammation has recently been observed in patients with fibromyalgia. Limited research has examined the relationships between neuroinflammation and conditions that co-occur with fibromyalgia, such as sleep disturbance, stress, cognitive impairment, and psychological disorders. To improve our understanding of fibromyalgia and the differences in patients' symptom experiences, this study will measure neuroinflammation in brain regions associated with fibromyalgia and examine how neuroinflammation relates to differences in fibromyalgia-related pain, sleep disturbance, stress, cognitive impairment, and psychological well-being. This study can provide valuable information about the causes of fibromyalgia, which can help inform new treatments or modify existing treatments to reduce the impact of fibromyalgia on patients' lives.
Programme
Doctoral Research Award: Canada Graduate Scholarships
Emplacement
Ontario, Canada
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
518481
Name
Millar Kayla A
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Musculoskeletal Health and Arthritis
Theme2
Clinical
Prcname2
Doctoral Research Awards - B
Projecttitle
The Role of Neuroinflammation in Clinical Presentations of Fibromyalgia
Programtype2
Studentship Programs
Orgnameinp2
Queen's University (Kingston, Ontario)
Cihramount2
$120,000
Cihrequipment2
$0
Programname2
Doctoral Research Award: Canada Graduate Scholarships
Keyworddelim
Chronic Pain; Fibromyalgia; Individual Differences; Magnetic Resonance Spectroscopy; Neuroinflammation
Abstract
Fibromyalgia is a medical condition characterized by chronic widespread pain, fatigue, sleep disturbance, cognitive impairment, and psychological disorders. These symptoms negatively affect patients' physical, psychological, and social well-being, including loss of employment, poor mental health, and social isolation, resulting in greatly reduced quality of life. Currently, there is no ideal treatment for fibromyalgia due to our limited understanding of its causes, and the differences in the symptoms and severity of symptoms that patients experience. Research suggests inflammation in the nervous system or, neuroinflammation, can contribute to the development and maintenance of chronic pain conditions. Importantly, neuroinflammation has recently been observed in patients with fibromyalgia. Limited research has examined the relationships between neuroinflammation and conditions that co-occur with fibromyalgia, such as sleep disturbance, stress, cognitive impairment, and psychological disorders. To improve our understanding of fibromyalgia and the differences in patients' symptom experiences, this study will measure neuroinflammation in brain regions associated with fibromyalgia and examine how neuroinflammation relates to differences in fibromyalgia-related pain, sleep disturbance, stress, cognitive impairment, and psychological well-being. This study can provide valuable information about the causes of fibromyalgia, which can help inform new treatments or modify existing treatments to reduce the impact of fibromyalgia on patients' lives.
Competitiondate
202411
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Millar, Kayla A
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $120,000~ $0~