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Grant: CIHR New Investigator

Université de Montréal

$300,000.00

Role of the Phosphoinositides and Moesin on the Actin/Microtubule crosstalk during cell division.

EF 2011-12

Résumé
The aim of this project is to understand the molecular basis underlying how cell division is deregulated in cancer cells. This study will be performed using drosophila fly as a model using modern genetic and cell biology tools to identify and characterize novel genes involved in the control of cell division. In the last past years, Drosophila melanogaster has proven to be an excellent model organism to study such aspects of cell biology. Since most of the molecular functions are conserved throughout evolution, this work will provide new avenues to study the process of cell division across species. Deregulation of cell division being one of the major causes leading to cancer and metastasis, this work will enable a better understanding on the molecular pathways that prevent this disease.
Programme
CIHR New Investigator
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
241168
Name
Carreno Sébastien
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Genetics
Theme2
Biomedical
Prcname2
New Investigators C
Projecttitle
Role of the Phosphoinositides and Moesin on the Actin/Microtubule crosstalk during cell division.
Programtype2
Salary Programs
Orgnameinp2
Université de Montréal
Cihramount2
$300,000
Cihrequipment2
$0
Programname2
CIHR New Investigator
Keyworddelim
Actin; Cell Division; Drosophila; Functional Genomics; Microscopy; Microtubule
Abstract
The aim of this project is to understand the molecular basis underlying how cell division is deregulated in cancer cells. This study will be performed using drosophila fly as a model using modern genetic and cell biology tools to identify and characterize novel genes involved in the control of cell division. In the last past years, Drosophila melanogaster has proven to be an excellent model organism to study such aspects of cell biology. Since most of the molecular functions are conserved throughout evolution, this work will provide new avenues to study the process of cell division across species. Deregulation of cell division being one of the major causes leading to cancer and metastasis, this work will enable a better understanding on the molecular pathways that prevent this disease.
Competitiondate
201109
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Carreno, Sébastien
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $300,000~ $0~