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Grant: Project Grant

University of Calgary

$1,055,700.00

Epicardial Adipose Tissue-Derived Stem Cells in Myocardial Infarction: Investigating the Influence of Diabetes

EF 2023-24

Résumé
Our dedicated team of researchers is currently delving into a promising solution to tackle the heart damage caused by diabetes-induced myocardial damage. Our focus is on exploring the potential therapeutic benefits of epicardial adipose tissue-derived stem cells (EAT-SCs) in aiding cardiac repair and angiogenesis. These specialized cells are located around the heart and have been found to play a crucial role in maintaining heart health. Our main objective is to conduct a comprehensive and thorough study of EAT-SCs and their function in normal heart activity, as well as their response under diabetic conditions. With our findings, we aim to create innovative and tailored therapies that can effectively repair damaged hearts caused by diabetes. This groundbreaking research has the potential to make a significant impact in the fight against cardiovascular diseases.
Programme
Project Grant
Bénéficiaire
Emplacement
Alberta, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
501786
Name
Patel Vaibhav B
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Circulatory and Respiratory Health
Theme2
Biomedical
Prcname2
Cardiovascular System - A: Cells and Tissues
Projecttitle
Epicardial Adipose Tissue-Derived Stem Cells in Myocardial Infarction: Investigating the Influence of Diabetes
Programtype2
Operating Grants
Orgnameinp2
University of Calgary
Cihramount2
$1,055,700
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Angiogenesis; Cardiac Repair; Epicardial Adipose Tissue; Fibrosis; Myocardial Infarction; Secretome; Stem Cells
Abstract
Our dedicated team of researchers is currently delving into a promising solution to tackle the heart damage caused by diabetes-induced myocardial damage. Our focus is on exploring the potential therapeutic benefits of epicardial adipose tissue-derived stem cells (EAT-SCs) in aiding cardiac repair and angiogenesis. These specialized cells are located around the heart and have been found to play a crucial role in maintaining heart health. Our main objective is to conduct a comprehensive and thorough study of EAT-SCs and their function in normal heart activity, as well as their response under diabetic conditions. With our findings, we aim to create innovative and tailored therapies that can effectively repair damaged hearts caused by diabetes. This groundbreaking research has the potential to make a significant impact in the fight against cardiovascular diseases.
Competitiondate
202403
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Patel, Vaibhav B; Fedak, Paul William M
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $1,055,700~ $0~