Grant: Project Grant

Blood delivers oxygen to the brain through the smallest pipes or our vascular system, the capillaries. When the brain becomes inflamed, some of these pipes get blocked, creating a traffic jam for red blood cells which are responsible for oxygen transport. In early stages of diseases, these jams are temporary and to date, we don't know how a transient blockage will affect the brain. In this work, we will develop new technology that can measure the jams and oxygen delivery at faster rates than possible before. This will allow investigation of the role of transient jams on the brain.