Grant: Emerging Team Grant: Co-morb of brain disorders & other health problems-full

Mechanisms of inflammation may be involved with a host of comorbid disorders affecting behaviour. In the aging brain, inflammatory mechanisms may interact with diseased blood vessels and diminished brain reserve capacity to result in problems of learning and memory, and in depression. In younger adults, inflammatory mechanisms may be an integral part of the way exposure to viral infections can influence thinking, memory and mental illnesses such as schizophrenia or bipolar disorder. Better understanding of the risk factors for viral infection may also be important in limiting the prevalence of comorbid mental illness, addiction and infectious disease.