Grant: Operating Grant: COVID-19 Rapid Research Funding Opportunity - Therapeutics
McMaster University
$1,089,205.00
Awake Prone Position in Hypoxemic Patients with Coronavirus Disease 19
EF 2020-21
Résumé
Coronavirus disease (COVID-19) can cause low oxygen levels and life-threatening lung failure. Many COVID-19 patients will need treatment in the Intensive Care Unit (ICU) with life support and a breathing machine. A possible treatment that could stop patients in hospital from developing lung failure is prone positioning. Prone positioning is when a patient lays on their stomach and rests for several hours. The risks of prone positioning in COVID-19 are not known. We designed a clinical trial to test if prone positioning before patients need life support can prevent death or the need for a breathing machine. Patients with COVID-19 and low oxygen levels will be treated with either prone positioning or normal positioning. The clinical trial will be performed at 34 hospitals across Canada, Saudi Arabia, and Mexico. If prone positioning saves patients' lives or prevents the need for breathing machines, it will be used in hospitals across Canada and around the world.
Programme
Operating Grant: COVID-19 Rapid Research Funding Opportunity - Therapeutics
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
429678
Name
Alhazzani Waleed
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Circulatory and Respiratory Health
Theme2
Clinical
Prcname2
COVID-19 Rapid Research - Therapeutics
Projecttitle
Awake Prone Position in Hypoxemic Patients with Coronavirus Disease 19
Programtype2
Operating Grants
Orgnameinp2
McMaster University
Cihramount2
$1,089,205
Cihrequipment2
$0
Programname2
Operating Grant: COVID-19 Rapid Research Funding Opportunity - Therapeutics
Keyworddelim
Acute Respiratory Distress Syndrome (Ards); Coronavirus; Non-Invasive Mechanical Ventilation; Proning
Abstract
Coronavirus disease (COVID-19) can cause low oxygen levels and life-threatening lung failure. Many COVID-19 patients will need treatment in the Intensive Care Unit (ICU) with life support and a breathing machine. A possible treatment that could stop patients in hospital from developing lung failure is prone positioning. Prone positioning is when a patient lays on their stomach and rests for several hours. The risks of prone positioning in COVID-19 are not known. We designed a clinical trial to test if prone positioning before patients need life support can prevent death or the need for a breathing machine. Patients with COVID-19 and low oxygen levels will be treated with either prone positioning or normal positioning. The clinical trial will be performed at 34 hospitals across Canada, Saudi Arabia, and Mexico. If prone positioning saves patients' lives or prevents the need for breathing machines, it will be used in hospitals across Canada and around the world.
Competitiondate
202005
Approvedterm2
0 yr 6 mths
Pinamesdelim
Alhazzani, Waleed; Cook, Deborah J; Parhar, Ken Kuljit S; Stelfox, Henry T; Weatherald, Jason
Approvedterm
0 an 6 mois
Cihrcontribution2
~ $1,089,205~ $0~
